1: allyl bromide With indium in N,N-dimethyl-formamide 0.666667 h; 2: methoxycarbonyl cyanide; acetic anhydride in tetrahydrofuran; N,N-dimethyl-formamide 2 h; 3: With triethylamine in tetrahydrofuran; N,N-dimethyl-formamide

1: 81 percent / n-BuLi / tetrahydrofuran; hexane / 1.) -78 deg C, 20 min, 2.) -78 deg C, 3 h; room temperature, 1 h 2: 75 percent / 0.2 M TFA / acetonitrile / 120 h / Ambient temperature 3: 144 mg / DMAP / CH2Cl2 / Ambient temperature View Scheme

1: 75 percent / 0.2 M TFA / acetonitrile / 120 h / Ambient temperature 2: 144 mg / DMAP / CH2Cl2 / Ambient temperature View Scheme

4-(N,N-dimethlyamino)pyridine in dichloromethane Ambient temperature;