2-氨基-5-甲氧基苯甲酰胺合成路线 （共 10 条）
反应条件
hydrogen; palladium 10 on activated carbon in methanol T=20°C; P=760.051 Torr; 6 h;
参考文献
Takeda Pharmaceutical Company Limited
Patent: EP1953148 A1, 2008 ;
Location in patent: Page/Page column 128-129 ;
EP 1953148 A1
反应条件
ethanol; iron; ammonium chloride
参考文献
Journal of Organic Chemistry, , vol. 21, p. 939,941
反应条件
ammonia; water T=20°C; 1 h;
参考文献
SMITHKLINE BEECHAM CORPORATION
Patent: WO2009/20990 A1, 2009 ;
Location in patent: Page/Page column 70 ;
WO 2009/020990 A1
反应条件
1: NH3(g) / benzene / 20 °C 2: H2 / 10percent Pd/C / methanol / 6 h View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 43, # 23 p. 4479 - 4487
反应条件
ammonium hydroxide in tetrahydrofuran 6 h;
参考文献
Cheng, Xu; Vellalath, Sreekumar; Goddard, Richard; List, Benjamin
Journal of the American Chemical Society, 2008 , vol. 130, # 47 p. 15786 - 15787
反应条件
ethanol; iron; ammonium chloride
参考文献
Journal of Organic Chemistry, , vol. 21, p. 939,941
反应条件
1: aqueous ethanol 2: iron; NH4Cl; aqueous ethanol View Scheme
参考文献
Journal of Organic Chemistry, , vol. 21, p. 939,941
反应条件
mercury-cathode Electrolysis;
参考文献
Bulletin de la Societe Chimique de France, , p. 2365,2372
反应条件
potassium hydroxide Hydrolysis;
参考文献
Bergmann; Bentov
Journal of Organic Chemistry, 1955 , vol. 20, p. 1654
反应条件
T=160°C; 0.333333 h; Microwave irradiation;
参考文献
MILLENNIUM PHARMACEUTICALS, INC.
Patent: WO2006/71875 A1, 2006 ;
Location in patent: Page/Page column 91 ;
WO 2006/071875 A1
