1: 82 percent / diisopropylethylamine / dioxane / 20 h / 50 °C 2: 94 percent / H2 / Pd(OH)2 / methanol / 72 h / 760 Torr / Ambient temperature 3: NaIO4, RuCl3*H2O / acetonitrile; CCl4; H2O / 2 h View Scheme

1: 82 percent / diisopropylethylamine / dioxane / 20 h / 50 °C 2: 94 percent / H2 / Pd(OH)2 / methanol / 72 h / 760 Torr / Ambient temperature 3: NaIO4, RuCl3*H2O / acetonitrile; CCl4; H2O / 2 h 4: 1.) 3N HCl, 2.) Dowex 50*8 / 1.) THF, room temperature, 2 h. View Scheme