1: With chloro-trimethyl-silane; copper(I) thiophene-2-carboxylate; (R)-p-tol-BINAP in diethyl ether T=-78°C; Inert atmosphere; 2: With hydrogenchloride in methanol; diethyl ether; water Inert atmosphere; optical yield given as percent eeenantioselective reaction;
L-phenylalanine; copper dichloride in water T=180°C; 0.333333 h; Inert atmosphere;
参考文献
Adams, An; Bouckaert, Capucine; Van Lancker, Fien; De Meulenaer, Bruno; De Kimpe, Norbert
Journal of Agricultural and Food Chemistry, 2011 , vol. 59, # 20 p. 11058 - 11062
