188290-36-0合成路线 （共 917 条）
反应条件
1: thiophene With 2,2,6,6-tetramethyl-piperidine; n-butyllithium; CdCl2*TMEDA in tetrahydrofuran; hexane T=0 - 20°C; Inert atmosphere; 2: 1-bromo-4-methoxy-benzene With 1,1'-bis(diphenylphosphino)ferrocene; palladium diacetate in tetrahydrofuran; hexane 18 h; Inert atmosphereReflux; chemoselective reaction;
参考文献
Snegaroff, Katia; L'Helgoual'ch, Jean-Martial; Bentabed-Ababsa, Ghenia; Nguyen, Tan Tai; Chevallier, Floris; Yonehara, Mitsuhiro; Uchiyama, Masanobu; Derdour, Aicha; Mongin, Florence
Chemistry - A European Journal, 2009 , vol. 15, # 39 p. 10280 - 10290
反应条件
potassium tert-butylate in dimethyl sulfoxide T=20°C; 3 h; Schlenk techniqueInert atmosphereIrradiation; TimeTemperatureConcentrationReagent/catalyst; Overall yield = 90 percent;
参考文献
Buden, Maria E.; Guastavino, Javier F.; Rossi, Roberto A.
Organic Letters, 2013 , vol. 15, # 6 p. 1174 - 1177
反应条件
1: thiophene With n-butyllithium in tetrahydrofuran T=-75°C; 1 h; Inert atmosphere; 2: With zinc(II) chloride−TMEDA in tetrahydrofuran T=-75 - 20°C; 3: 1-bromo-4-methoxy-benzene Further stages;
参考文献
Seggio, Anne; Jutand, Anny; Priem, Ghislaine; Mongin, Florence
Synlett, 2008 , # 19 p. 2955 - 2960
反应条件
manganese triacetate Heating;
参考文献
Demir, Ayhan S.; Reis, Oemer; Emrullahoglu, Mustafa
Journal of Organic Chemistry, 2003 , vol. 68, # 2 p. 578 - 580
反应条件
manganese triacetate Heating;
参考文献
Demir, Ayhan S.; Reis, Oemer; Emrullahoglu, Mustafa
Tetrahedron, 2002 , vol. 58, # 40 p. 8055 - 8058
反应条件
18-crown-6 ether; potassium acetate
参考文献
Ellames, George J; Gibson, Jennifer S; Herbert, John M; McNeill, Alan H
Tetrahedron, 2001 , vol. 57, # 46 p. 9487 - 9497
反应条件
in water; acetonitrile Photolysis; Product distribution; Further Variations:Solvents;
参考文献
Manet, Ilse; Monti, Sandra; Grabner, Gottfried; Protti, Stefano; Dondi, Daniele; Dichiarante, Valentina; Fagnoni, Maurizio; Albini, Angelo
Chemistry - A European Journal, 2008 , vol. 14, # 3 p. 1029 - 1039
反应条件
in water; acetonitrile Photolysis; Product distribution; Further Variations:Solvents;
参考文献
Manet, Ilse; Monti, Sandra; Grabner, Gottfried; Protti, Stefano; Dondi, Daniele; Dichiarante, Valentina; Fagnoni, Maurizio; Albini, Angelo
Chemistry - A European Journal, 2008 , vol. 14, # 3 p. 1029 - 1039
反应条件
Amberlyst 15 cation-exchange resin T=25°C; 15 h;
参考文献
Iovel', I. G.; Gol'dberg, Yu. Sh.; Shimanskaya, M. V.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1989 , vol. 25, # 6 p. 613 - 616
Khimiya Geterotsiklicheskikh Soedinenii, 1989 , vol. 25, # 6 p. 746 - 749
反应条件
sulfuric acid; iodine; iodic acid in tetrachloromethane; water; acetic acid 100 h; Heating;
参考文献
D'Auria, Maurizio; Distefano, Claudio; D'Onofrio, Franco; Mauriello, Giacomo; Racioppi, Rocco
Journal of the Chemical Society, Perkin Transactions 1, 2000 , # 20 p. 3513 - 3518
