188290-36-0合成路线 （共 917 条）
反应条件
oxygen; trimethylamine in gas gas-phase methylation of furan and thiophene, pressure dependence, effect of partial pressure of NMe3, competition experiments in the presence of benzene; mechanism of methylation; Product distribution;
参考文献
Angelini, Giancarlo; Lilla, Gaetano; Speranza, Maurizio
Journal of the American Chemical Society, 1982 , vol. 104, # 25 p. 7091 - 7098
反应条件
oxygen; trimethylamine in gas gas-phase methylation of furan and thiophene, pressure dependence, effect of partial pressure of NMe3, competition experiments in the presence of benzene; mechanism of methylation; Product distribution;
参考文献
Angelini, Giancarlo; Lilla, Gaetano; Speranza, Maurizio
Journal of the American Chemical Society, 1982 , vol. 104, # 25 p. 7091 - 7098
反应条件
isopentyl nitrite T=70 - 80°C;
参考文献
Vernin,G.; Metzger,J.
Journal of Organic Chemistry, 1975 , vol. 40, p. 3183 - 3189
反应条件
tin(IV) chloride in dichloromethane T=23°C; Friedel-Crafts reaction; 2.5 h;
参考文献
Zhao, Weili; Carreira, Erick M.
Chemistry - A European Journal, 2007 , vol. 13, # 9 p. 2671 - 2688
反应条件
trifluoromethanesulfonic acid 2-pyridinyl ester; trifluoroacetic acid 4 h; Heating;
参考文献
Keumi, Takashi; Yoshimura, Kiichiro; Shimada, Masakazu; Kitajima, Hidehiko
Bulletin of the Chemical Society of Japan, 1988 , vol. 61, p. 455 - 460
反应条件
hydrogenchloride T=0°C; 0.333333 h;
参考文献
Hou, Jianhui; Tan, Zhan'ao; Yan, Yong; He, Youjun; Yang, Chunhe; Li, Yongfang
Journal of the American Chemical Society, 2006 , vol. 128, # 14 p. 4911 - 4916
反应条件
1: formaldehyd With hydrogenchloride in water T=60°C; 2: thiophene in water T=25 - 30°C; 0.333333 h;
参考文献
CIBA HOLDING INC.
Patent: WO2008/101806 A2, 2008 ;
Location in patent: Page/Page column 31-33 ;
参考文献
Cagniant
Bulletin de la Societe Chimique de France, 1949 , p. 847,851
反应条件
1: thiophene With sodium; polyethylene; isoprene in tetrahydrofuran; toluene T=-1 - 1°C; 3.5 h; 2: oxirane in tetrahydrofuran; toluene T=19 - 21°C; 2 h; 3: With water; ammonium chloride in tetrahydrofuran; toluene T=0 - 22°C; 0.25 h; Cooling with ice-methanol bath; Product distribution / selectivity;
参考文献
Sanofi-Synthelabo
Patent: US6639083 B1, 2003 ;
Location in patent: Page/Page column 5 ;
反应条件
1: thiophene With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 2: ethylene glycol cyclic sulfate in tetrahydrofuran; hexane T=-78 - 20°C; 3: With sulfuric acid in tetrahydrofuran; hexane 3 h; Heating; Further stages.;
参考文献
Schlaeger, Torsten; Oberdorf, Christoph; Tewes, Bastian; Wuensch, Bernhard
Synthesis, 2008 , # 11 p. 1793 - 1797
