188290-36-0合成路线 （共 917 条）
反应条件
NiCl2(PCy3)2 in diethyl ether; toluene T=80°C; Wenkert synthesis; 36 h; Inert atmosphere;
参考文献
Hintermann, Lukas; Schmitz, Marco; Chen, Yun
Advanced Synthesis and Catalysis, 2010 , vol. 352, # 14-15 p. 2411 - 2415
反应条件
chlorine anschliessend mit heisser Alkalilauge behandeln;
参考文献
Coonradt et al.
Journal of the American Chemical Society, 1948 , vol. 70, p. 2564,2565
反应条件
chlorine anschliessend Behandlung mit heisser Alkalilauge;
参考文献
Journal of the American Chemical Society, , vol. 70, p. 2564,2565
反应条件
1: thiophene With n-butyllithium; N,N,N',N,-tetramethylethylenediamine in tetrahydrofuran; hexane T=20°C; 2 h; 2: With zinc(II) chloride in tetrahydrofuran; hexane 1 h; Heating; 3: 1-bromo-4-ethenylbenzene With tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran 15 h; Heating;
参考文献
Fauvel, Anne; Deleuze, Herve; Landais, Yannick
European Journal of Organic Chemistry, 2005 , # 18 p. 3900 - 3910
反应条件
1: thiophene With n-butyllithium in tetrahydrofuran T=-78°C; 1 h; Inert atmosphere; 2: tri-isopropoxy-borane in tetrahydrofuran T=-78 - 20°C; 2.5 h; Inert atmosphere; 3: 2,3-dimethylbutane-2,3-diol in tetrahydrofuran 0.5 h; Inert atmosphere;
参考文献
Trippe-Allard, Gaelle; Lacroix, Jean-Christophe
Tetrahedron, 2013 , vol. 69, # 2 p. 861 - 866
反应条件
in octane T=25°C; 4 h; Conversion of starting material;
参考文献
Mitsubishi Rayon Co., Ltd.
Patent: EP1481978 A1, 2004 ;
Location in patent: Page 10 ;
反应条件
catalyst: [Ir(COD)Cl]2/2bpy in further solvent(s) under Ar; thiophene (60 mmol) added to pinacolborane (2 mmol) + 1.5 molpercent(Ir(COD)Cl)2 + 1.5 molpercent bpy; stirred (80°C, 6 h); solvent removed (vac., room temp.); residue chromd. (silica gel, CH2Cl2); elem. anal.;
参考文献
Mertins, Kristin; Zapf, Alexander; Beller, Matthias
Journal of Molecular Catalysis A: Chemical, 2004 , vol. 207, # 1 p. 21 - 25
反应条件
1: thiophene With n-butyllithium in tetrahydrofuran T=20°C; 0.5 h; 2: 2-isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane in tetrahydrofuran T=20°C; 0.333333 h; Further stages.;
参考文献
Dienes, Yvonne; Durben, Stefan; Karpati, Tamas; Neumann, Toni; Englert, Ulli; Nyulaszi, Laszlo; Baumgartner, Thomas
Chemistry - A European Journal, 2007 , vol. 13, # 26 p. 7487 - 7500
反应条件
1: thiophene With n-butyllithium in tetrahydrofuran T=-78°C; 1 h; Inert atmosphere; 2: With tri-isopropoxy-borane in tetrahydrofuran T=-78 - 20°C; 2.5 h; Inert atmosphere; 3: 2,3-dimethylbutane-2,3-diol in tetrahydrofuran T=20°C; 0.5 h; Inert atmosphere;
参考文献
Trippé-Allard, Gaëlle; Lacroix, Jean-Christophe
Patent: US2013/79529 A1, 2013 ;
Location in patent: Paragraph 0148; 0149; 0150; 0151; 0152; 0153; 0154 ;
反应条件
di-μ-chloro-bis(η4-1,5-cyclooctadiene)diiridium; 4,4'-di-tert-butyl-2,2'-dipyridyl in octane T=80°C; 16 h;
参考文献
Takagi, Jun; Sato, Kazuaki; Hartwig, John F; Ishiyama, Tatsuo; Miyaura, Norio
Tetrahedron Letters, 2002 , vol. 43, # 32 p. 5649 - 5651
