188290-36-0合成路线 （共 917 条）
反应条件
1: thiophene With n-butyllithium in tetrahydrofuran T=-78°C; 2: PinBOH in tetrahydrofuran T=-78°C;
参考文献
Lim, Kimin; Ju, Myung Jong; Na, Jongbeom; Choi, Hyeju; Song, Min Young; Kim, Byeonggwan; Song, Kihyung; Yu, Jong-Sung; Kim, Eunkyoung; Ko, Jaejung
Chemistry - A European Journal, 2013 , vol. 19, # 29 p. 9442 - 9446
反应条件
tert.-butylnitrite 2 h; Irradiation;
参考文献
Julliard,M. et al.
Helvetica Chimica Acta, 1978 , vol. 61, p. 2941 - 2948
反应条件
1: thiophene With n-butyllithium in tetrahydrofuran; hexane T=-78°C; Metallation; 0.75 h; 2: With copper(l) iodide in tetrahydrofuran; hexane T=-20°C; transmetallation; 2 h; 3: iodomethylphosphonic acid diethyl ester in tetrahydrofuran; hexane T=20°C; Alkylation;
参考文献
Wang, Chuanguang; Dalton, Larry R.
Tetrahedron Letters, 2000 , vol. 41, # 5 p. 617 - 620
反应条件
1: thiophene; formaldehyd With hydrogen bromide; acetic acid T=5 - 20°C; 2: triethyl phosphite Arbuzov reaction; 1 h; Heating;
参考文献
Journal of Organic Chemistry, , vol. 70, # 15 p. 6004 - 6017
反应条件
chlorine; iron(III) chloride in tetrachloromethane T=30°C; 10 h;
参考文献
Journal of Heterocyclic Chemistry, , vol. 32, # 3 p. 791 - 796
反应条件
chlorine anschliessend Erhitzen auf 190grad;
参考文献
Coonradt et al.
Journal of the American Chemical Society, 1948 , vol. 70, p. 2564,2565
反应条件
N-chloro-succinimide in acetic acid Chlorination; 2 h; Heating;
参考文献
Journal of the Chemical Society. Perkin Transactions 2, , # 7 p. 1453 - 1458
反应条件
chlorine T=550 - 600°C;
参考文献
Hurd; Anderson
Journal of the American Chemical Society, 1953 , vol. 75, p. 3517
反应条件
potassium carbonate in dichloromethane 10 h; Ambient temperatureIrradiation; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Seki, Koh-ichi; Ohkura, Kazue; Terashima, Masanao; Kanaoka, Yuichi
Heterocycles, 1984 , vol. 22, # 10 p. 2347 - 2350
反应条件
potassium carbonate in dichloromethane 10 h; Ambient temperatureIrradiation; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Seki, Koh-ichi; Ohkura, Kazue; Terashima, Masanao; Kanaoka, Yuichi
Heterocycles, 1984 , vol. 22, # 10 p. 2347 - 2350
