188290-36-0合成路线 （共 917 条）
反应条件
aluminium trichloride
1) (CH2)Cl2, -30 deg C, 1 h, RT, 2 d; 3) reflux, (CH2)Cl2; Yield given. Multistep reaction;
参考文献
Belen'kii, L. I.; Yakubov, A. P.
Tetrahedron, 1986 , vol. 42, # 2 p. 759 - 762
反应条件
Ir2(COD)2(SnCl3)2Cl2(μ-Cl)2
T=90°C; Friedel-Crafts alkylation; 0.25 h;
参考文献
Rueping, Magnus; Nachtsheim, Boris J.; Ieawsuwan, Winai
Advanced Synthesis and Catalysis, 2006 , vol. 348, # 9 p. 1033 - 1037
反应条件
K10-ZnCl2 in dichloromethane
T=40°C; 1.5 h;
参考文献
Clark, Peter D.; Kirk, Andrew; Mesher, Shaun T.; Yee, James G.K.
Phosphorus, Sulfur and Silicon and the Related Elements, 1994 , vol. 96, # 1-4 p. 441 - 444
反应条件
bismuth trifluoromethanesulphonate in nitromethane
Friedel-Crafts-type benzylation; 5 h; Heating;
参考文献
Rueping, Magnus; Nachtsheim, Boris J.; Ieawsuwan, Winai
Advanced Synthesis and Catalysis, 2006 , vol. 348, # 9 p. 1033 - 1037
反应条件
iron(III) chloride
T=100°C; Friedel-Crafts reaction; 12 h; Title compound not separated from byproducts.;
参考文献
Wang, Bi-Qin; Xiang, Shi-Kai; Sun, Zuo-Peng; Guan, Bing-Tao; Hu, Ping; Zhao, Ke-Qing; Shi, Zhang-Jie
Tetrahedron Letters, 2008 , vol. 49, # 27 p. 4310 - 4312
反应条件
boron trifluoride diethyl etherate
T=120°C; 2 h; Overall yield = 75 percent;
参考文献
Li, Yu; Xiong, Yan; Li, Xueming; Ling, Xuege; Huang, Ruofeng; Zhang, Xiaohui; Yang, Jianchun
Green Chemistry, 2014 , vol. 16, # 6 p. 2976 - 2981
反应条件
1: thiophene With 2-Chloro-2-methylpropane; lithium in tetrahydrofuran
0.75 h; sonication;
2: thiophene-2-carbaldehyde in tetrahydrofuran
1 h;
参考文献
Sanchez, Muriel; Diallo, Ousmane; Oussaid, Adyl; Oussaid, Boualem; Garrigues, Bernard
Phosphorus, Sulfur and Silicon and Related Elements, 2001 , vol. 173, p. 235 - 242
反应条件
1: thiophene With n-butyllithium; N,N,N',N,-tetramethylethylenediamine in hexane
1 h; Heating;
2: thiophene-2-carbaldehyde in tetrahydrofuran; hexane
T=0°C; 0.25 h;
参考文献
Gupta, Iti; Hung, C.-Hsiung; Ravikanth, Mangalampalli
European Journal of Organic Chemistry, 2003 , # 22 p. 4392 - 4400
反应条件
sodium amalgam; bromobenzene; diethyl ether
anschliessend Behandeln mit Thiophen-2-carbaldehyd und mit wss. Ammoniumchlorid-Loesung;
参考文献
Van Zyl et al.
Journal of the American Chemical Society, 1956 , vol. 78, p. 1955,1956
反应条件
bis(η4-1,5-cyclooctadiene)-di-μ-methoxy-diiridium(I) in cyclohexane
(Schlenk, N2 atm.) the soln. in cyclohexane was stirred at room temp. overnight; Kugelrohr distillation;
参考文献
Boller, Timothy M.; Murphy, Jaclyn M.; Hapke, Marko; Ishiyama, Tatsuo; Miyaura, Norio; Hartwig, John F.
Journal of the American Chemical Society, 2005 , vol. 127, # 41 p. 14263 - 14278
