188290-36-0合成路线 （共 917 条）
参考文献
Biedermann; Jacobson
Chemische Berichte, 1886 , vol. 19, p. 2445
反应条件
zinc in toluene
T=70°C; Acylation; 8 h;
参考文献
Meshram; Reddy, Gondi Sudershan; Muralidhar Reddy; Yadav
Synthetic Communications, 1998 , vol. 28, # 12 p. 2203 - 2206
反应条件
trifluoromethanesulfonic acid 2-pyridinyl ester; trifluoroacetic acid
4 h; Heating;
参考文献
Keumi, Takashi; Yoshimura, Kiichiro; Shimada, Masakazu; Kitajima, Hidehiko
Bulletin of the Chemical Society of Japan, 1988 , vol. 61, p. 455 - 460
参考文献
Kaye et al.
Journal of the American Chemical Society, 1953 , vol. 75, p. 745
反应条件
aluminium trichloride in carbon disulfide
1.) RT, 13.5 h, 2.) reflux, 3 h;
参考文献
McKean, D. R.; Parrinello, G.; Renaldo, A. F.; Stille, J. K.
Journal of Organic Chemistry, 1987 , vol. 52, # 3 p. 422 - 424
反应条件
[2,2']bipyridinyl; (1S)-10-camphorsulfonic acid; water; palladium diacetate
T=110°C; 36 h;
参考文献
Jiang, Tao-Shan; Wang, Guan-Wu
Advanced Synthesis and Catalysis, 2014 , vol. 356, # 2-3 p. 369 - 373
反应条件
1.) glow discharge, 2.) -196 deg C -> -80 deg C; Multistep reaction. Title compound not separated from byproducts;
参考文献
Skramstad, Jan; Chaudhry, Mohammed Shoaib; Garvang, Arne
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1984 , vol. 38, # 6 p. 509 - 512
反应条件
1: thiophene With n-butyllithium; N,N,N',N,-tetramethylethylenediamine in hexane
T=0°C; 1 h; Cooling with ice;
2: acetone in tetrahydrofuran; hexane
T=0°C; 0.25 h; Cooling with ice;
参考文献
Gupta, Iti; Froehlich, Roland; Ravikanth, Mangalampalli
European Journal of Organic Chemistry, 2008 , # 11 p. 1884 - 1900
反应条件
silver fluoride; PdCl2(PPh2(CH2)4PPh2) in dimethyl sulfoxide
T=60°C; 5 h;
参考文献
Masui, Kentaro; Mori, Atsunori; Okano, Kunihiko; Takamura, Kenji; Kinoshita, Motoi; Ikeda, Tomiki
Organic Letters, 2004 , vol. 6, # 12 p. 2011 - 2014
反应条件
1: thiophene With 2,2,6,6-tetramethyl-piperidine; n-butyllithium; CdCl2*TMEDA in tetrahydrofuran; hexane
T=0 - 20°C; Inert atmosphere;
2: 1-bromo-4-methoxy-benzene With 1,1'-bis(diphenylphosphino)ferrocene; palladium diacetate in tetrahydrofuran; hexane
18 h; Inert atmosphereReflux; chemoselective reaction;
参考文献
Snegaroff, Katia; L'Helgoual'ch, Jean-Martial; Bentabed-Ababsa, Ghenia; Nguyen, Tan Tai; Chevallier, Floris; Yonehara, Mitsuhiro; Uchiyama, Masanobu; Derdour, Aicha; Mongin, Florence
Chemistry - A European Journal, 2009 , vol. 15, # 39 p. 10280 - 10290
