2-氮杂双环[2.2.1]-5-庚烯-2-羧酸叔丁酯合成路线 （共 12 条）
反应条件
sodium hydroxide; borane; dihydrogen peroxide; potassium carbonate in tetrahydrofuran; water; ethyl acetate
参考文献
Eli Lilly and Company
Patent: US6124312 A1, 2000 ;
US 6124312 A
反应条件
1.1: O3; AcOH / CH2Cl2 / -78 °C 1.2: dimethyl sulfide / CH2Cl2 / -78 - 20 °C 1.3: 77 percent / NaCNBH3 / methanol / 24 h / 20 °C 2.1: H2 / Pd(OH)2/C / methanol / 36 h / 50 °C / 3102.97 Torr View Scheme
参考文献
Targacept, Inc.
Patent: US2011/263629 A1, 2011 ;
US 20110263629 A1
