6-硝基-2-甲基苯甲腈合成路线 （共 26 条）
反应条件
hydrogenchloride; sodium nitrite in sodium hydrogencarbonate; ethyl acetate; toluene
参考文献
TEIJIN LIMITED
Patent: US2005/267148 A1, 2005 ;
反应条件
Pd0(tris(tert-butyl)phosphine)2; zinc in N,N-dimethyl acetamide T=95°C; 4 h;
参考文献
Littke, Adam; Soumeillant, Maxime; Kaltenbach III, Robert F.; Cherney, Robert J.; Tarby, Christine M.; Kiau, Susanne
Organic Letters, 2007 , vol. 9, # 9 p. 1711 - 1714
反应条件
hydrogenchloride; potassium tert-butylate in N-methyl-acetamide
反应条件
hydrogenchloride; sodium nitrite 1.) glacial AcOH, H2O, -10 deg C, 30 min, 2.) H2O, C6H6, 25 deg C, 1 h; 70-75 deg C, 1 h; Yield given. Multistep reaction;
参考文献
Bioorganic and Medicinal Chemistry, , vol. 6, # 6 p. 643 - 659
反应条件
(i) NaNO2, aq. HCl, (ii) /BRN= 4652394/, CuSO4, (iii) NO2/HNO3; Multistep reaction;
参考文献
Helvetica Chimica Acta, , vol. 43, p. 104 - 113
反应条件
1: sulfuric acid 2: potassium nitrite; sulfuric acid 3: ferrosulfate; ammonia View Scheme
参考文献
Newman,M.S.; Kannan,R.
Journal of Organic Chemistry, 1976 , vol. 41, # 21 p. 3356 - 3359
反应条件
1: tin (II)-chloride; hydrochloric acid; glacial acetic acid / <50 3: chlorine / 200 °C 4: alcohol 5: sulfuric acid / beim Destillieren View Scheme
参考文献
Kenner; Witham
Journal of the Chemical Society, 1921 , vol. 119, p. 1460
反应条件
1: sulfuric acid 2: potassium nitrite; sulfuric acid 3: ferrosulfate; ammonia 4: acetic acid anhydride; sodium acetate / nachfolgend Oxydation mit Permanganat in alkalischer Loesung und Verseifen des Reaktionsproduktes View Scheme
参考文献
Gabriel; Thieme
Chemische Berichte, 1919 , vol. 52, p. 1083
反应条件
hydrogenchloride; iron in methanol 0.25 h; Heating;
参考文献
Klaubert, Dieter H.; Sellstedt, John H.; Guinosso, Charles J.; Capetola, Robert J.; Bell, Stanley C.
Journal of Medicinal Chemistry, 1981 , vol. 24, # 6 p. 742 - 748
参考文献
Gabriel; Thieme
Chemische Berichte, 1919 , vol. 52, p. 1083
