6-硝基-2-甲基苯甲腈合成路线 （共 26 条）
反应条件
1: hydriodic acid; red phosphorus View Scheme
参考文献
Gabriel; Thieme
Chemische Berichte, 1919 , vol. 52, p. 1083
反应条件
1: sulfuric acid 2: potassium nitrite; sulfuric acid 3: thionyl chloride 4: diethyl ether View Scheme
参考文献
Chemische Berichte, , vol. 52, p. 1083
反应条件
1: 69 percent / cyclohexene / palladium on charcoal / ethanol / 3 h / Heating 2: 60 percent / bis-(2-methoxy-ethyl) ether / 3 h / 130 - 140 °C View Scheme
参考文献
Harris, Neil V.; Smith, Christopher; Bowden, Keith
Journal of Medicinal Chemistry, 1990 , vol. 33, # 1 p. 434 - 444
反应条件
1: sulfuric acid 2: potassium nitrite; sulfuric acid 3: thionyl chloride View Scheme
参考文献
Gabriel; Thieme
Chemische Berichte, 1919 , vol. 52, p. 1083
反应条件
1: 2-methyl-6-nitrobenzonitrile With iron(III) chloride; hydrazine hydrate in methanol; water 3 h; Heating; 2: formic acid With hydrogenchloride in water T=90 - 130°C; Further stages.;
参考文献
Chandregowda, Venkateshappa; Venkateswara Rao, Gudapati; Chandrasekara Reddy, Goukanapalli
Heterocycles, 2007 , vol. 71, # 1 p. 39 - 48
反应条件
1: sulfuric acid 2: potassium nitrite; sulfuric acid 3: ferrosulfate; ammonia 4: 210 °C View Scheme
参考文献
Gabriel; Thieme
Chemische Berichte, 1919 , vol. 52, p. 1083
反应条件
1: tin (II)-chloride; hydrochloric acid; glacial acetic acid / <50 3: sulfuric acid / 100 - 110 °C View Scheme
参考文献
Kenner; Witham
Journal of the Chemical Society, 1921 , vol. 119, p. 1460
反应条件
(i) aq. H2SO4, (ii) aq. NaNO2; Multistep reaction;
参考文献
Helvetica Chimica Acta, , vol. 43, p. 104 - 113
反应条件
1: tin (II)-chloride; hydrochloric acid; glacial acetic acid / <50 View Scheme
参考文献
Journal of the Chemical Society, , vol. 119, p. 1460
反应条件
1: tin (II)-chloride; hydrochloric acid; glacial acetic acid / <50 3: sulfuric acid / 100 - 110 °C 4: sodium nitrite View Scheme
参考文献
Kenner; Witham
Journal of the Chemical Society, 1921 , vol. 119, p. 1460
