hydrogenchloride in methanol

1: 1.) EtMgBr, 2.) CuCl / 1.) THF, from 50 deg C to 60 deg C, 1 h, 2.) THF, 60 deg C, 1 h 2: HCl, MeOH 3: pyridine 4: NaI, Me3SiCl / acetonitrile 5: 1.) LiN(i-Pr)2, 2.) HMPA 6: H2, quinoline / Pd/BaSO4 / ethyl acetate 7: lithium t-butyl thiolate / dimethylformamide View Scheme