4-氨基-5-(甲酰氨基甲基)-2-甲基嘧啶合成路线 （共 32 条）
参考文献
Chatterji; Anand
Journal of Scientific and Industrial Research, 1959 , vol. 18B, p. 272,277
Full Text Show Details
Evans; Robertson
Australian Journal of Chemistry, 1973 , vol. 26, p. 1599,1600, 1604
反应条件
sodium hydroxide; water in methanol T=66.84 - 75.84°C; 4.5 h; Product distribution / selectivity;
参考文献
WO2006/79504 A2, ;
Page/Page column 11; 19-20; 24 ;
反应条件
sodium hydroxide T=75°C; 3 h; Inert atmosphere;
参考文献
Letinois, Ulla; Schuetz, Jan; Haerter, Ralph; Stoll, Rinke; Huffschmidt, Florian; Bonrath, Werner; Karge, Reinhard
Organic Process Research and Development, 2013 , vol. 17, # 3 p. 427 - 431
反应条件
tetraphosphorus decasulfide; toluene
参考文献
Matsukawa
Yakugaku Zasshi, 1942 , vol. 62, p. 417,443;dtsch.Ref.S.122,125
Chem.Abstr., 1951 , p. 4724
Full Text Show Details
I.G.Farbenind.
Patent: DE685032 , 1936 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 24, p. 446
Full Text Show Details
Andersag; Westphal
Chemische Berichte, 1937 , vol. 70, p. 2035,2044
反应条件
sodium hydroxide; water in methanol T=66.84 - 75.84°C; 4.5 h; Product distribution / selectivity;
参考文献
WO2006/79504 A2, ;
Page/Page column 11; 19-20; 24 ;
参考文献
Takeda Chobei Shoten,K.K.
Patent: US2184720 , 1938 ;
反应条件
1: 2-methyl-4-amino-5-formylaminomethyl pyrimidine With formic acid
RefluxInert atmosphere;
2: 3-Mercapto-4-oxopentyl Acetate Reflux; Overall yield = 84.8 percentChromat.;
参考文献
DSM IP ASSETS B.V.; PENG, Kun; DAI, Xixiang; ZHAO, Lizhi; CAO, Weifeng; LETINOIS, Ulla
Patent: WO2014/29320 A1, 2014 ;
Location in patent: Page/Page column 8 ;
反应条件
1: toluene; P2S5
View Scheme
参考文献
Andersag; Westphal
Chemische Berichte, 1937 , vol. 70, p. 2035,2044
参考文献
Matsukawa; Yurugi
Yakugaku Zasshi, 1949 , vol. 69, p. 508,509
Chem.Abstr., 1950 , p. 4476
参考文献
Matsukawa; Iwatsu; Yurugi
Yakugaku Zasshi, 1948 , vol. 68, p. 286
Chem.Abstr., 1951 , p. 9545
