4,4'-二甲基-反-二苯乙烯合成路线 （共 112 条）
反应条件
titanium tetrachloride; zinc McMurry coupling;
参考文献
Feast; Loevenich; Puschmann; Taliani
Chemical Communications, 2001 , # 5 p. 505 - 506
反应条件
lithium hydroxide monohydrate; C21H18N4O2Pd; tetrabutylammomium bromide in N,N-dimethyl acetamide T=160°C; Heck reaction; 44 h;
参考文献
Srinivas, Pottabathula; Likhar, Pravin R.; Maheswaran, Hariharasarma; Sridhar, Balasubramanian; Ravikumar, Krishnan; Kantam, Mannepalli Lakshmi
Chemistry - A European Journal, 2009 , vol. 15, # 7 p. 1578 - 1581
反应条件
potassium carbonate; bis(dibenzylideneacetone)-palladium(0); 3-(2,6-diisopropylphenyl)-1-(2-diphenylphosphanylbenzyl)-3H-imidazol-1-ium chloride in N,N-dimethyl acetamide T=140°C; Heck reaction; 12 h;
参考文献
Wang, Ai-E; Xie, Jian-Hua; Wang, Li-Xin; Zhou, Qi-Lin
Tetrahedron, 2005 , vol. 61, # 1 p. 259 - 266
反应条件
potassium carbonate in water; N,N-dimethyl-formamide T=70°C; Heck Reaction; 0.133333 h; Microwave irradiationGreen chemistry;
参考文献
Keesara, Srinivas; Parvathaneni, Saiprathima; Dussa, Govardhan; Mandapati, Mohan Rao
Journal of Organometallic Chemistry, 2014 , vol. 765, p. 31 - 38
反应条件
Grubb's 2nd generation catalyst in dichloromethane 2 h; Heating;
参考文献
Poeylaut-Palena, Andres A.; Testero, Sebastian A.; Mata, Ernesto G.
Journal of Organic Chemistry, 2008 , vol. 73, # 5 p. 2024 - 2027
反应条件
1: 4-methyl-benzaldehyde; diazomethyl-trimethyl-silane With triphenylphosphine; copper(l) chloride in tetrahydrofuran; isopropyl alcohol T=60°C; 2: para-bromotoluene With triethylamine; palladium diacetate; tris-(o-tolyl)phosphine T=100°C; Heck cross-coupling; Further stages.;
参考文献
Lebel, Helene; Ladjel, Chehla; Brethous, Lise
Journal of the American Chemical Society, 2007 , vol. 129, # 43 p. 13321 - 13326
反应条件
Grubb's 2nd generation catalyst in dichloromethane T=43°C; Cross Metathesis; 22 h; Inert atmosphere;
参考文献
Tetrahedron Letters, , vol. 54, # 10 p. 1211 - 1217
反应条件
p-toluenesulfinic acid sodium salt; potassium hydroxide in dimethyl sulfoxide T=100°C; 16 h;
参考文献
Zhao, Feng; Luo, Jiaying; Tan, Qi; Liao, Yunfeng; Peng, Shengming; Deng, Guo-Jun
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 10 p. 1914 - 1918
反应条件
p-toluenesulfinic acid sodium salt; potassium hydroxide in dimethyl sulfoxide T=100°C; 16 h;
参考文献
Zhao, Feng; Luo, Jiaying; Tan, Qi; Liao, Yunfeng; Peng, Shengming; Deng, Guo-Jun
Advanced Synthesis and Catalysis, 2012 , vol. 354, # 10 p. 1914 - 1918
反应条件
1: 2Br(1-)*C30H34NP(2+) With sodium hydride in ethylene glycol dimethyl ether T=0°C; Wittig reaction; 1 h; Inert atmosphere; 2: 4-methyl-benzaldehyde in ethylene glycol dimethyl ether T=60°C; Wittig reaction; 10 h; Inert atmosphere; optical yield given as percent dediastereoselective reaction;
参考文献
Tetrahedron, , vol. 67, # 5 p. 951 - 957
