(R)-1-(4-苄氧基-3-硝基苯基)-2-溴乙醇合成路线 （共 17 条）
反应条件
oxazaborolidine from cis (1R,2S)-aminoindanol and trimethylboroxine; borane in tetrahydrofuran T=-15°C;
参考文献
Hett, Robert; Fang, Qun Kevin; Gao, Yun; Hong, Yaping; Butler, Hal T.; Nie, Xiaoyi; Wald, Stephen A.
Tetrahedron Letters, 1997 , vol. 38, # 7 p. 1125 - 1128
反应条件
borane in tetrahydrofuran
反应条件
sodium formate; Triton X-100; (R,R)-TsDPEN; [{(η5-C5Me5)RhCl}2(μ-Cl)2] in water T=28°C; 6 h; Title compound not separated from byproducts;
参考文献
Wang, Fei; Liu, Hui; Cun, Linfeng; Zhu, Jin; Deng, Jingen; Jiang, Yaozhong
Journal of Organic Chemistry, 2005 , vol. 70, # 23 p. 9424 - 9429
反应条件
1.1: 82 percent / Br2 / CHCl3 / 25 °C 2.1: BH3*THF / tetrahydrofuran / -20 °C 2.2: 48 percent / lipase PS; vinyl acetate / various solvent(s) / 72 h / 37 °C View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 11, # 13 p. 2705 - 2717
反应条件
1.1: N-ethyl-N,N-diisopropylamine / acetonitrile / 20 °C 1.2: 3 h / 20 °C / Reflux 2.1: tetra-n-butylammonium tribromide / tetrahydrofuran; methanol / 4 h 3.1: BH3*N,N-diethylanilline; (1R,2S)-1-amino-2,3-dihydro-1H-inden-2-ol / tetrahydrofuran / 3.5 h / 3 - 5 °C View Scheme
参考文献
Organic Process Research and Development, , vol. 15, # 6 p. 1247 - 1255
反应条件
boron trifluoride-tetrahydrofuran complex; (-)-(1R,2S)-1-amino-2-hydroxy-1,2,3,4-tetrahydronaphthalene in tetrahydrofuran T=0°C; 2 h; other reag., other temp.; Product distribution;
参考文献
Tetrahedron Letters, , vol. 39, # 13 p. 1705 - 1708
