in dichloromethane; N,N-dimethyl-formamide

oxalyl dichloride; N,N-dimethyl-formamide in dichloromethane T=20°C; Chlorination; 4 h;

1: 88 percent / NaOEt / ethanol / 72 h / 20 °C 2: 27 percent / POCl3 / 1 h / Heating 3: 78 percent / aq. NaOH / 3 h / 20 °C 4: 61 percent / (COCl)2; DMF / CH2Cl2 / 4 h / 20 °C View Scheme

1: 78 percent / aq. NaOH / 3 h / 20 °C 2: 61 percent / (COCl)2; DMF / CH2Cl2 / 4 h / 20 °C View Scheme