2,4-二三氟甲基-5-嘧啶甲酸乙酯合成路线 （共 3 条）
反应条件
sodium ethanolate in ethanol Condensation; cyclization; 24 h; Heating;
参考文献
Palanki; Erdman; Gayo-Fung; Shevlin; Sullivan; Goldman; Ransone; Bennett; Manning; Suto
Journal of medicinal chemistry, 2000 , vol. 43, # 21 p. 3995 - 4004
反应条件
sodium hydroxide in ethanol
参考文献
Signal Pharmaceuticals, Inc.
Patent: US5811428 A1, 1998 ;
反应条件
sodium hydroxide in ethanol T=20°C; Hydrolysis; 1 h;
参考文献
Palanki; Erdman; Gayo-Fung; Shevlin; Sullivan; Goldman; Ransone; Bennett; Manning; Suto
Journal of medicinal chemistry, 2000 , vol. 43, # 21 p. 3995 - 4004
