2,4-双-(三氟甲基)嘧啶-5-羧酸合成路线 （共 3 条）
反应条件
sodium hydroxide in ethanol
参考文献
Signal Pharmaceuticals, Inc.
Patent: US5811428 A1, 1998 ;
反应条件
sodium hydroxide in ethanol T=20°C; Hydrolysis; 1 h;
参考文献
Palanki; Erdman; Gayo-Fung; Shevlin; Sullivan; Goldman; Ransone; Bennett; Manning; Suto
Journal of medicinal chemistry, 2000 , vol. 43, # 21 p. 3995 - 4004
反应条件
1: 39 percent / NaOEt / ethanol / 24 h / Heating 2: 25 percent / aq. NaOH / ethanol / 1 h / 20 °C View Scheme
参考文献
Journal of medicinal chemistry, , vol. 43, # 21 p. 3995 - 4004
