hydrogenchloride in diethyl ether T=0°C; 2 h;

<b>Multi-step reaction with 2 steps<br /> </b>1: 5 Pd(II)/C(eggshell); hydrogen / ethanol / 8 h / 20 &deg;C / 7500.75 Torr<br />2: (S)-α-hydroxybenzeneacetic acid / ethyl acetate / 4 h / Reflux; Resolution of racemate<br /> <br /> &nbsp;

<b>Multi-step reaction with 4 steps<br /> </b>1: 5 Pd(II)/C(eggshell); hydrogen<br />2: acetonitrile / 12 h / Reflux<br />3: 5 Pd(II)/C(eggshell); hydrogen / ethanol / 8 h / 20 &deg;C / 7500.75 Torr<br />4: (S)-α-hydroxybenzeneacetic acid / ethyl acetate / 4 h / Reflux; Resolution of racemate<br /> <br /> &nbsp;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '2208678', constants.ctx, '0')">(S)-α-hydroxybenzeneacetic acid</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '506104', constants.ctx, '0')">ethyl acetate</a> <br />4&nbsp;h;&nbsp;&nbsp;RefluxResolution of racemate;&nbsp;&nbsp;optical yield given as percent ee;&nbsp;<br /> &nbsp;