1: 91 percent / AlCl3 / acetonitrile / 0.5 h / Ambient temperature 2: 90 percent / K2CO3 / methanol / 1.5 h / Heating 3: 90 percent / H2 / 10percent Pd/C / methanol; ethyl acetate / Ambient temperature View Scheme

<b>Multi-step reaction with 8 steps<br /> </b>1: 100 percent / conc. HCl, acetic acid / 1 h / Ambient temperature<br />2: 83 percent / K₂CO₃, KI / acetone; dimethylformamide / Heating<br />3: 75 percent / AlBr₃, NaI / acetonitrile / 0.25 h / 0 &deg;C<br />4: pyridine / 2 h / 70 - 80 &deg;C<br />5: KOH / pyridine / 80 &deg;C<br />6: 87 percent / conc. H₂SO₄, acetic acid / 1 h / 50 &deg;C<br />7: 71 percent / dimethyldioxirane / acetone / 0 &deg;C<br />8: 96 percent / K₂CO₃ / acetone / Heating<br /> <br /> &nbsp;

<b>Multi-step reaction with 6 steps<br /> </b>1: 75 percent / AlBr₃, NaI / acetonitrile / 0.25 h / 0 &deg;C<br />2: pyridine / 2 h / 70 - 80 &deg;C<br />3: KOH / pyridine / 80 &deg;C<br />4: 87 percent / conc. H₂SO₄, acetic acid / 1 h / 50 &deg;C<br />5: 71 percent / dimethyldioxirane / acetone / 0 &deg;C<br />6: 96 percent / K₂CO₃ / acetone / Heating<br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: 71 percent / dimethyldioxirane / acetone / 0 &deg;C<br />2: 96 percent / K₂CO₃ / acetone / Heating<br /> <br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1: 87 percent / conc. H₂SO₄, acetic acid / 1 h / 50 &deg;C<br />2: 71 percent / dimethyldioxirane / acetone / 0 &deg;C<br />3: 96 percent / K₂CO₃ / acetone / Heating<br /> <br /> &nbsp;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '4267587', constants.ctx, '0')">potassium carbonate</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '635680', constants.ctx, '0')">acetone</a> <br />&nbsp;Heating;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 9 steps<br /> </b>1: K₂CO₃ / dimethylformamide / 0.17 h / 150 &deg;C<br />2: 100 percent / conc. HCl, acetic acid / 1 h / Ambient temperature<br />3: 83 percent / K₂CO₃, KI / acetone; dimethylformamide / Heating<br />4: 75 percent / AlBr₃, NaI / acetonitrile / 0.25 h / 0 &deg;C<br />5: pyridine / 2 h / 70 - 80 &deg;C<br />6: KOH / pyridine / 80 &deg;C<br />7: 87 percent / conc. H₂SO₄, acetic acid / 1 h / 50 &deg;C<br />8: 71 percent / dimethyldioxirane / acetone / 0 &deg;C<br />9: 96 percent / K₂CO₃ / acetone / Heating<br /> <br /> &nbsp;