hydrogenchloride in hydrogenchloride T=80°C; 0.5 h; Acid hydrolysis;

1: 75 percent / triphenylphosphine; diethyl azodicarboxylate / dioxane / 18 h / 20 °C 2: 85 percent / NaOH / methanol / 3 h / 20 °C 3: 90 percent / N-chlorosuccinimide; Na2SO3; Na2CO3 / AgNO3 / acetonitrile; CH2Cl2 / 0.33 h / 25 °C 4: HCl / HCl / 0.5 h / 80 °C / Acid hydrolysis View Scheme

1: 90 percent / N-chlorosuccinimide; Na2SO3; Na2CO3 / AgNO3 / acetonitrile; CH2Cl2 / 0.33 h / 25 °C 2: HCl / HCl / 0.5 h / 80 °C / Acid hydrolysis View Scheme

1: 85 percent / NaOH / methanol / 3 h / 20 °C 2: 90 percent / N-chlorosuccinimide; Na2SO3; Na2CO3 / AgNO3 / acetonitrile; CH2Cl2 / 0.33 h / 25 °C 3: HCl / HCl / 0.5 h / 80 °C / Acid hydrolysis View Scheme