delta-N-乙酰基-delta-N-羟基-L-鸟氨酸合成路线 (共 2 条)
反应条件
hydrogenchloride; hydrogen; palladium on activated charcoal 1.) reflux, 2 h; 2.) H2O, 25 deg C, 7 h; Multistep reaction;
参考文献
Benz
1984 , vol. 1984, # 8 p. 1424 - 1433
反应条件
Multi-step reaction with 4 steps 1: 81 percent / Zn, AcOH / 3 h / Irradiation2: 100 percent / trifluoroacetic acid / 0.5 h / Ambient temperature3: tetrahydrofuran / 22 h / Ambient temperature4: 87 percent / H2 / 10percent Pd/C / methanol; H2O / 4 h
参考文献
Dolence, E. Kurt; Lin, Chia-En; Miller, Marvin J.; Payne, Shelley M. Journal of Medicinal Chemistry, 1991 , vol. 34, # 3 p. 956 - 968