1-[4-(甲硫基)苯基]-1,4-戊烷二酮合成路线 （共 2 条）
反应条件
3-ethyl-5-(2-hydroxyethyl)-4-methyl-1,3-thiazolium bromide; triethylamine T=70°C; Stetter reaction; P=3102.97 Torr; 0.25 h; Microwave irradiation;
参考文献
Battilocchio, Claudio; Poce, Giovanna; Alfonso, Salvatore; Porretta, Giulio Cesare; Consalvi, Sara; Sautebin, Lidia; Pace, Simona; Rossi, Antonietta; Ghelardini, Carla; Di Cesare Mannelli, Lorenzo; Schenone, Silvia; Giordani, Antonio; Di Francesco, Luigia; Patrignani, Paola; Biava, Mariangela
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 13 p. 3695 - 3701
反应条件
1: 90 percent / aq. Oxone(R) / methanol / 2 h / 25 °C 2: 85 percent / p-toluenesulfonic acid / toluene / 20 h / Heating View Scheme
参考文献
Khanna, Ish K.; Weier, Richard M.; Yu, Yi; Collins, Paul W.; Miyashiro, Julie M.; Koboldt, Carol M.; Veenhuizen, Amy W.; Currie, Jerry L.; Seibert, Karen; Isakson, Peter C.
Journal of Medicinal Chemistry, 1997 , vol. 40, # 11 p. 1619 - 1633
