1-Boc-4-乙氧基羰基甲氧基哌啶合成路线 （共 4 条）
反应条件
dirhodium tetraacetate in dichloromethane
参考文献
Scarborough, Robert M.; Mehrotra, Mukund; Pandey, Anjali; Smyth, Mark
Patent: US2003/55244 A1, 2003 ;
反应条件
1: 1-(tert-Butyloxycarbonyl)-4-piperidinol With sodium hydride in N,N-dimethyl-formamide T=20°C; 2 h; 2: ethyl bromoacetate in N,N-dimethyl-formamide T=20°C; 2 h;
参考文献
Kaneko, Toshihiko; Clark, Richard S. J.; Ohi, Norihito; Ozaki, Fumihiro; Kawahara, Tetsuya; Kamada, Atsushi; Okano, Kazuo; Yokohama, Hiromitsu; Ohkuro, Masayoshi; Muramoto, Kenzo; Takenaka, Osamu; Kobayashi, Seiichi
Chemical and Pharmaceutical Bulletin, 2004 , vol. 52, # 6 p. 675 - 687
参考文献
Scarborough, Robert M.; Mehrotra, Mukund; Pandey, Anjali; Smyth, Mark
Patent: US2003/55244 A1, 2003 ;
反应条件
lithium hydroxide in methanol; water Hydrolysis;
参考文献
Peschke, Bernd; Ankersen, Michael; Sehested Hansen, Birgit; Kruse Hansen, Thomas; Langeland Johansen, Nils; Lau, Jesper; Madsen, Kjeld; Petersen, Hans; Thogersen, Henning; Watson, Brett
European Journal of Medicinal Chemistry, 1999 , vol. 34, # 5 p. 363 - 380
