4-[(4-羟基-2-嘧啶基)氨基]苯腈合成路线 （共 4 条）
反应条件
pyridine hydrochloride T=150 - 160°C; 3 h;
参考文献
WO2012/147091 A2, ;
Page/Page column 7-8 ;
反应条件
in diethylene glycol dimethyl ether
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 17 p. 2235 - 2239
反应条件
1: trichlorophosphate / 1.5 h / 0 - 20 °C / Reflux 2: toluene-4-sulfonic acid / 1,4-dioxane / 14 h / 100 - 110 °C View Scheme
参考文献
HETERO RESEARCH FOUNDATION; PARTHASARADHI REDDY, Bandi; RATHNAKAR REDDY, Kura; MURALIDHARA REDDY, Dasari; VENKAT NARSIMHA REDDY, Adulla; VAMSI KRISHNA, Bandi
Patent: WO2012/147091 A2, 2012 ;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 17 p. 2235 - 2239
