1: With pyridine T=5 - 35°C; 60 h; Industry scale; 2: With sulfuric acid T=30°C; Industry scale;

potassium hydroxide; water T=130 - 140°C; 7 h;

Catalyst M-Chromium oxide; sulfuric acid

1: 23 percent / ethanolamine, CuCl / 2-methyl-propan-2-ol / 24 h / Heating 2: 96 percent / KOH, deionized H2O / 7 h / 130 - 140 °C View Scheme

barium dihydroxide; silver nitrate

1: diluted Cr2O3-H2SO4 2: AgNO3; aq. barium hydroxide solution View Scheme

暂无反应条件数据

sulfuric acid; magnesium sulfate in benzene Heating; Yield given;

1.1: sulfuric acid / n-heptane / 18 h / 19 - 25 °C / Industry scale; Sealed vessel 2.1: n-hexyl lithium / n-heptane; tetrahydrofuran / 0.5 h / -65 - -55 °C / Industry scale 2.2: 1.5 h / -65 - -55 °C / Industry scale 3.1: (+)-CSO / n-heptane; tetrahydrofuran / 6 h / -65 - -55 °C / Industry scale 3.2: -60 - -40 °C / Industry scale 4.1: trifluoroacetic acid / toluene / 25.5 h / 50 °C / Industry scale 4.2: 15 - 20 °C / pH 5 - 6 / Industry scale 5.1: N-ethyl-N,N-diisopropylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / 2-methyl tetrahydrofuran / 0.08 h / 0 - 10 °C / Industry scale 5.2: 4 h / 0 - 35 °C / Industry scale 6.1: hydrogen; acetic acid / palladium on carbon / methanol / 7 h / 60 °C / 4137.29 Torr / Industry scale 7.1: hydrogenchloride / water; tert-butyl methyl ether / 3 °C / Industry scale; Reflux 8.1: N-ethyl-N,N-diisopropylamine; benzotriazol-1-ol; N'-(3-dimethylaminopropyl)-N-ethylcarbodiimide / ethyl acetate; acetonitrile; water / -5 - 30 °C / Industry scale 9.1: sodium acetate; sodium hypochlorite; acetic acid; 2,2,6,6-tetramethyl-1-piperidinyloxy, free radical / methyl acetate; water; tert-butyl methyl ether / 2 h / 5 - 15 °C / Industry scale View Scheme

hydrogen fluoride; N-bromoacetamide