4-氯乙酰基哌嗪-1-羧酸叔丁酯合成路线 （共 4 条）
反应条件
triethylamine in tetrahydrofuran T=0 - 20°C; 21 h;
参考文献
RIGEL PHARMACEUTICALS, INC.
Patent: WO2007/30680 A2, 2007 ;
Location in patent: Page/Page column 157 ;
WO 2007/030680 A2
参考文献
Isis Pharmaceuticals, Inc.
Patent: US6191273 B1, 2001 ;
反应条件
triethylamine in dichloromethane; water
参考文献
G. D. Searle and Co.
Patent: US5753660 A1, 1998 ;
反应条件
1: N-ethyl-N,N-diisopropylamine / dichloromethane / 20 h / 27 °C 2: N-ethyl-N,N-diisopropylamine View Scheme
参考文献
CHANG, Zee-Fen; HU, Chun-Mei; FANG, Jim-Min; YEH, Ming-Tyng
Patent: WO2012/72019 A1, 2012 ;
WO 2012/072019 A1
