potassium hydroxide; [{Rh(C2H4)2Cl}2]; (1R)-endo-(+)-fenchol biphenol phosphite in 1,4-dioxane; water T=23°C; 15 h;

chloroform; palladium diacetate; caesium carbonate; triphenylphosphine in toluene T=80°C; 40 h; Inert atmosphere;

(trimethylsilyl)methylzinc iodide; 1-methyl-pyrrolidin-2-one; n-butyllithium; trimethylsilyl bromide 1) pentane, THF, -90 deg C, 1 h; 2) THF, pentane, -30 deg C, 1 h; 3) THF, pentane, -30 deg C, 2 h, rt, overnight; Yield given. Multistep reaction;