4-乙酰氨基-3-碘苯甲酸甲酯合成路线 （共 7 条）
反应条件
pyridine T=0 - 20°C; 16.5 h; Inert atmosphere;
参考文献
RVX Therapeutics Inc.; McLure, Kevin G.; Young, Peter R.
Patent: US2013/281399 A1, 2013 ;
Location in patent: Paragraph 0561; 0580 ;
反应条件
sulfuric acid T=20°C; 0.0833333 h;
参考文献
Kotha, Sambasivarao; Shah, Vrajesh R.
European Journal of Organic Chemistry, 2008 , # 6 p. 1054 - 1064
反应条件
1: 6.5 g / BTMA-ICl2 / acetic acid; CH2Cl2 2: 6.2 g / acetic acid View Scheme
参考文献
Fagnola, Maria Chiara; Candiani, Ilaria; Visentin, Giuseppina; Cabri, Walter; Zarini, Franco; Mongelli, Nicola; Bedeschi, Angelo
Tetrahedron Letters, 1997 , vol. 38, # 13 p. 2307 - 2310
反应条件
1: 6.2 g / acetic acid View Scheme
参考文献
Fagnola, Maria Chiara; Candiani, Ilaria; Visentin, Giuseppina; Cabri, Walter; Zarini, Franco; Mongelli, Nicola; Bedeschi, Angelo
Tetrahedron Letters, 1997 , vol. 38, # 13 p. 2307 - 2310
参考文献
Fagnola, Maria Chiara; Candiani, Ilaria; Visentin, Giuseppina; Cabri, Walter; Zarini, Franco; Mongelli, Nicola; Bedeschi, Angelo
Tetrahedron Letters, 1997 , vol. 38, # 13 p. 2307 - 2310
反应条件
1: With copper(l) iodide; Na2S*9H2O in N,N-dimethyl-formamide T=80°C; 12 h; 2: With hydrogenchloride in N,N-dimethyl-formamide T=20°C;
参考文献
Ma, Dawei; Xue, Peng; Jiang, Yongwen; Xie, Siwei; Zhang, Xiaojing; Dong, Jinhua
Angewandte Chemie, International Edition, 2009 , vol. 48, # 23 p. 4222 - 4225
反应条件
copper(l) iodide; TMG; bis-triphenylphosphine-palladium(II) chloride in 1,4-dioxane
T=80°C; 18 h;
参考文献
Fagnola, Maria Chiara; Candiani, Ilaria; Visentin, Giuseppina; Cabri, Walter; Zarini, Franco; Mongelli, Nicola; Bedeschi, Angelo
Tetrahedron Letters, 1997 , vol. 38, # 13 p. 2307 - 2310
