1: isobutyric acid ethyl ester With lithium diisopropyl amide in tetrahydrofuran; hexanes T=-78°C; 0.5 h; 2: 6-heptenyl bromide With N,N,N',N',N'',N''-hexamethylphosphoric triamide in tetrahydrofuran; hexanes T=-78 - 20°C; 16 h;

1: With methanol; lithium hydroxide; water in tetrahydrofuran T=50°C; 17.5 h; 2: With hydrogenchloride; water pH=3;