2-乙基-3-甲基-1H-吲哚合成路线 （共 40 条）
反应条件
palladium diacetate; tetrabutyl-ammonium chloride; potassium carbonate; triphenylphosphine in N,N-dimethyl-formamide
T=100°C; 24 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Larock; Yum; Refvik
Journal of Organic Chemistry, 1998 , vol. 63, # 22 p. 7652 - 7662
反应条件
tri-ruthenium(0)dodecacarbonyl; aniline hydrochloric acid
T=140°C;
参考文献
Tokunaga, Makoto; Ota, Mitsuru; Haga, Masa-aki; Wakatsuki, Yasuo
Tetrahedron Letters, 2001 , vol. 42, # 23 p. 3865 - 3868
反应条件
1: Br2/Et3N / CH2Cl2
2: p-TSA
3: 1) lithium diisopropylamide / 1) THF, -78 deg C; 2) THF
4: LiAlH4 / tetrahydrofuran
View Scheme
参考文献
Vice, Susan F.; Gross, Edward A.; Friesen, Richard W.; Dmitrienko, Gary I.
Tetrahedron Letters, 1982 , vol. 23, # 8 p. 829 - 832
反应条件
1: 1) lithium diisopropylamide / 1) THF, -78 deg C; 2) THF
2: LiAlH4 / tetrahydrofuran
View Scheme
参考文献
Vice, Susan F.; Gross, Edward A.; Friesen, Richard W.; Dmitrienko, Gary I.
Tetrahedron Letters, 1982 , vol. 23, # 8 p. 829 - 832
反应条件
1: 35 percent / CaO, LiCl, CuCl*2H2O / acetone; H2O / 1.) 2 h, 3 to 10 deg C, 2.) 2 h, 10 deg C to room temp., 3.) 2 h, room temp.
2: 53 percent / Fe, HOAc, NaOAc*2H2O / ethanol; H2O / 2 h / Heating
View Scheme
参考文献
Raucher, Stanley; Koolpe, Gary A.
Journal of Organic Chemistry, 1983 , vol. 48, # 12 p. 2066 - 2069
反应条件
1: NaNO2 / H2O / 0.25 h / -5 - 2 °C
2: 35 percent / CaO, LiCl, CuCl*2H2O / acetone; H2O / 1.) 2 h, 3 to 10 deg C, 2.) 2 h, 10 deg C to room temp., 3.) 2 h, room temp.
3: 53 percent / Fe, HOAc, NaOAc*2H2O / ethanol; H2O / 2 h / Heating
View Scheme
参考文献
Raucher, Stanley; Koolpe, Gary A.
Journal of Organic Chemistry, 1983 , vol. 48, # 12 p. 2066 - 2069
反应条件
in ethanol
Fischer Indole Synthesis; RefluxAcidic conditions;
参考文献
Wu, Wei; Fan, Xin-Heng; Zhang, Li-Peng; Yang, Lian-Ming
RSC Advances, 2014 , vol. 4, # 7 p. 3364 - 3367
反应条件
mercaptoacetic acid in dichloromethane
Heating; Yield given;
参考文献
Vice, Susan F.; Friesen, Richard W.; Dmitrienko, Gary I.
Tetrahedron Letters, 1985 , vol. 26, # 2 p. 165 - 168
反应条件
acetic acid in dichloromethane
参考文献
Vice, Susan F.; Gross, Edward A.; Friesen, Richard W.; Dmitrienko, Gary I.
Tetrahedron Letters, 1982 , vol. 23, # 8 p. 829 - 832
反应条件
zinc trifluoromethanesulfonate
T=85°C; 5 h;
参考文献
Kumar, Manyam Praveen; Liu, Rai-Shung
Journal of Organic Chemistry, 2006 , vol. 71, # 13 p. 4951 - 4955
