(3S)-3-[(叔丁氧羰基)氨基]-3-苯基丙酸甲酯合成路线 （共 32 条）
反应条件
1.1: sodium hydride / tetrahydrofuran; various solvent(s) / 0.5 h / 0 °C 1.2: 82 percent / tetrahydrofuran; various solvent(s) / 2 h / 0 °C 2.1: 80 percent / tri-n-butyltin hydride; AIBN / toluene / Heating View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 18, # 17 p. 2099 - 2103
反应条件
1: palladium 10 on activated carbon; hydrogen / methanol / 96 h / 3102.97 Torr 2: sodium carbonate / dichloromethane; water / 20 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 78, # 6 p. 2511 - 2526
反应条件
1: formic acid / water; methanol / 20 °C / |Inert atmosphere 2: C34H15F10NO4S2 / toluene / 20 °C / |Inert atmosphere View Scheme
参考文献
Journal of the American Chemical Society, , vol. 135, # 41 p. 15334 - 15337
反应条件
1: formic acid / water; methanol / 20 °C / |Inert atmosphere 2: C34H15F10NO4S2 / toluene / 20 °C / |Inert atmosphere View Scheme
参考文献
Journal of the American Chemical Society, , vol. 135, # 41 p. 15334 - 15337
反应条件
in diethyl ether Yield given;
参考文献
Tetrahedron Letters, , vol. 35, # 10 p. 1589 - 1592
参考文献
Chemistry - A European Journal, , vol. 13, # 29 p. 8338 - 8351
反应条件
trifluoroacetic acid in dichloromethane
参考文献
Kim, Ronald M.; Chang, Jiang; Chapman, Kevin T.; Mills, Sander G.
Patent: US2002/193407 A1, 2002 ;
反应条件
1: 75 percent / diisobutylaluminium hydride / CH2Cl2 / -78 °C 2: 75 percent / Na(AcO)3BH / CH2Cl2 View Scheme
参考文献
Price, David A.; Gayton, Simon; Selby, Matthew D.; Ahman, Jens; Haycock-Lewandowski, Sarah; Stammen, Blanda L.; Warren, Andrew
Tetrahedron Letters, 2005 , vol. 46, # 30 p. 5005 - 5007
反应条件
lithium aluminium tetrahydride in tetrahydrofuran 2 h; Heating;
参考文献
Tetrahedron Asymmetry, , vol. 18, # 17 p. 2099 - 2103
反应条件
1: 75 percent / diisobutylaluminium hydride / CH2Cl2 / -78 °C 2: 75 percent / Na(AcO)3BH / CH2Cl2 3: 95 percent / CF3CO2H / CH2Cl2 4: 49 percent / polimer bound carbodiimide / CH2Cl2 / 1 h / 20 °C View Scheme
参考文献
Price, David A.; Gayton, Simon; Selby, Matthew D.; Ahman, Jens; Haycock-Lewandowski, Sarah; Stammen, Blanda L.; Warren, Andrew
Tetrahedron Letters, 2005 , vol. 46, # 30 p. 5005 - 5007
