(S)-γ-Valerolactone合成路线 （共 69 条）
反应条件
W-6 Raney Ni in methanol 6 h; Heating;
参考文献
White, James D.; Somers, Todd C.; Reddy, G. Nagabushana
Journal of Organic Chemistry, 1992 , vol. 57, # 18 p. 4991 - 4998
反应条件
hydrogen; platinum(IV) oxide in tetrahydrofuran 1.5 h;
参考文献
Brandaege, Svante; Jansbo, Kerstin; Minassie, Teclay
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1987 , vol. 41, # 10 p. 736 - 739
反应条件
hydrogenchloride; hydrogen; (S)-(-)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl; [Ru(η4-COD)(η3-methylallyl)2] in methanol; ethanol T=60°C; P=45600 - 53200 Torr; 6.5 h;
参考文献
Russian Chemical Bulletin, , vol. 54, # 10 p. 2374 - 2378
反应条件
hydrogenchloride; hydrogen; (S)-(-)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl; [Ru(η4-COD)(η3-methylallyl)2] in methanol; ethanol T=60°C; P=45600 - 53200 Torr; 5 h;
参考文献
Russian Chemical Bulletin, , vol. 54, # 10 p. 2374 - 2378
反应条件
pyridinium p-toluenesulfonate in methanol Heating;
参考文献
Garner, Philip; Anderson, James T.; Cox, Philip B.; Klippenstein, Stephen J.; Leslie, Ray; Scardovi, Noemi
Journal of Organic Chemistry, 2002 , vol. 67, # 17 p. 6195 - 6209
反应条件
Acetobacter aceti; glycerol in aq. phosphate buffer pH=5; 24 h; Microbiological reaction; Overall yield = 46 percent;
参考文献
Monatshefte fur Chemie, , vol. 144, # 5 p. 735 - 737
反应条件
1: With (Ph)2SiH2; bis(1,5-cyclooctadiene)-rhodium(I) tetrafluoroborate; (S,S)-2,2''-bis[(R)-1-(Et2P)ethyl]-1,1''-biferrocene in tetrahydrofuran T=-30°C; hydrosilylation; 31 h; 2: With hydrogenchloride in tetrahydrofuran; methanol T=0°C; Hydrolysis; lactonization; 1 h; Title compound not separated from byproducts;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 73, # 2 p. 485 - 496
反应条件
1: With lithium hydroxide in methanol T=20°C; 2: With hydrogenchloride in methanol; water T=70°C; Title compound not separated from byproducts;
参考文献
Tetrahedron Letters, , vol. 43, # 16 p. 2983 - 2986
反应条件
1.1: 76 percent / SOCl2 / 1 h 2.1: 77 percent / MCPBA / CH2Cl2 / 17 h 3.1: ethanol / 20 °C 4.1: aq. KOH / 4 h / Heating 5.1: 0.94 g / dimethylformamide / 24 h / 20 °C 6.1: porcine pancreatic lipase / diethyl ether / 39 h / 30 °C 6.2: tributyltin hydride; 1,1'-azobis(cyclohexanecarbonitrile) / toluene / 2 h / Heating View Scheme
参考文献
Synthetic Communications, , vol. 34, # 5 p. 817 - 828
反应条件
palladium on activated charcoal; hydrogen in ethyl acetate 5 h;
参考文献
Loza; Vostrikov; Miftakhov
Russian Journal of Organic Chemistry, 2008 , vol. 44, # 12 p. 1804 - 1806
