(S)-γ-Valerolactone合成路线 （共 69 条）
反应条件
dimethylsulfide; ozone 1) MeOH, -78 deg C, 3h, 2) a) -78 deg C, 1 h, b) room temp., 3 h; Yield given. Multistep reaction;
参考文献
Tetrahedron, , vol. 47, # 32 p. 6197 - 6214
反应条件
sulfuric acid Yield given;
参考文献
Chemistry Letters, , # 5 p. 843 - 846
反应条件
sodium methylate; lithium chloride 1) MeOH, reflux, 0.5 h; 2) MeOH, a) romm temp., overnight, b) 50 dceg C, 8 h, c) reflux, overnight; 3) DMSO, reflux, 3.5 h; Yield given. Multistep reaction;
参考文献
Tetrahedron, , vol. 48, # 15 p. 3139 - 3146
反应条件
lithium hydroxide; sodium tetrahydroborate; zinc(II) chloride 1.) THF, 2.) THF, room temperature; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Tetrahedron, , vol. 53, # 44 p. 15061 - 15068
反应条件
nickel; toluene-4-sulfonic acid 2.) benzene, reflux; Multistep reaction;
参考文献
Journal of the Chemical Society, Chemical Communications, , # 4 p. 211 - 213
反应条件
1: 1.) ZnCl2, 2.) i-Bu2AlH / 1.) THF, r.t., 0.5 h, 2.) toluene, -100 deg C, 0.6 h 2: 1.) Raney-Ni, 2.) p-TsOH / 2.) benzene, reflux View Scheme
参考文献
Journal of the Chemical Society, Chemical Communications, , # 4 p. 211 - 213
参考文献
Tetrahedron, , vol. 51, # 23 p. 6431 - 6442
参考文献
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), , # 10 p. 1759 - 1764
反应条件
1: iBu2AlH / hexane; tetrahydrofuran / -60 °C 2: (i) NaH, DMSO, (ii) /BRN= 1901134/ View Scheme
参考文献
Mori
Tetrahedron, 1975 , vol. 31, # 24 p. 3011 - 3012
