7-甲氧基-1H-4-喹啉酮合成路线 （共 12 条）
反应条件
in diphenylether; biphenyl T=220°C; 1.5 h;
参考文献
KIRIN BEER KABUSHIKI KAISHA
Patent: EP1724268 A1, 2006 ;
Location in patent: Page/Page column 46 ;
反应条件
sodium t-butanolate in 1,4-dioxane T=100°C; 4 h; Inert atmosphere;
参考文献
Huang, Jinkun; Chen, Ying; King, Anthony O.; Dilmeghani, Mina; Larsen, Robert D.; Faul, Margaret M.
Organic Letters, 2008 , vol. 10, # 12 p. 2609 - 2612
反应条件
palladium 10 on activated carbon; sodium hydroxide in water; isopropyl alcohol 16 h; Inert atmosphereReflux;
参考文献
Lange, Jens; Bissember, Alex C.; Banwell, Martin G.; Cade, Ian A.
Australian Journal of Chemistry, 2011 , vol. 64, # 4 p. 454 - 470
反应条件
T=160 - 600°C; P=0.0142514 Torr; 1 h; Inert atmosphereFlash vacuum pyrolysis; regioselective reaction;
参考文献
Hill, Lawrence; Imam, S. Haider; McNab, Hamish; O'Neill, William J.
Synlett, 2009 , # 11 p. 1847 - 1851
反应条件
tris-(dibenzylideneacetone)dipalladium(0); caesium carbonate; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene in 1,4-dioxane T=100°C; 24 h; Inert atmosphere;
参考文献
Huang, Jinkun; Chen, Ying; King, Anthony O.; Dilmeghani, Mina; Larsen, Robert D.; Faul, Margaret M.
Organic Letters, 2008 , vol. 10, # 12 p. 2609 - 2612
反应条件
tris-(dibenzylideneacetone)dipalladium(0); 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene in 1,4-dioxane T=100°C; 24 h; Inert atmosphere;
参考文献
Huang, Jinkun; Chen, Ying; King, Anthony O.; Dilmeghani, Mina; Larsen, Robert D.; Faul, Margaret M.
Organic Letters, 2008 , vol. 10, # 12 p. 2609 - 2612
反应条件
1: With hydrogenchloride; sodium hydroxide in methanol T=2.5°C; Reflux; 2: T=250 - 260°C;
参考文献
Yang, Donglai; Arifhodzic, Lejla; Ganellin, C. Robin; Jenkinson, Donald H.
European Journal of Medicinal Chemistry, 2013 , vol. 63, p. 907 - 923
反应条件
1: 17 percent / 600 °C / 0.01 Torr View Scheme
参考文献
Yang, Donglai; Arifhodzic, Lejla; Ganellin, C. Robin; Jenkinson, Donald H.
European Journal of Medicinal Chemistry, 2013 , vol. 63, p. 907 - 923
反应条件
1: copper(l) iodide; potassium carbonate / toluene / 20 h / 18 - 140 °C / Inert atmosphere; Sealed 2: trifluorormethanesulfonic acid / dichloromethane / 1 h / 0 - 18 °C / Inert atmosphere 3: palladium 10 on activated carbon; sodium hydroxide / water; isopropyl alcohol / 16 h / Inert atmosphere; Reflux View Scheme
参考文献
Lange, Jens; Bissember, Alex C.; Banwell, Martin G.; Cade, Ian A.
Australian Journal of Chemistry, 2011 , vol. 64, # 4 p. 454 - 470
反应条件
1: trifluorormethanesulfonic acid / dichloromethane / 1 h / 0 - 18 °C / Inert atmosphere 2: palladium 10 on activated carbon; sodium hydroxide / water; isopropyl alcohol / 16 h / Inert atmosphere; Reflux View Scheme
参考文献
Lange, Jens; Bissember, Alex C.; Banwell, Martin G.; Cade, Ian A.
Australian Journal of Chemistry, 2011 , vol. 64, # 4 p. 454 - 470
