2-(对甲苯氨基亚甲基)丙二酸二乙酯合成路线 (共 15 条)
反应条件
Gould-Jacob reaction; 0.0416667 h; Irradiation;
参考文献
Dave, Chaitanya G.; Joshipura, Hardik M.
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2002 , vol. 41, # 3 p. 650 - 652
反应条件
1: ethanol / 5 h / Heating 2: H2 / Pd/C / ethanol / Ambient temperature 3: diethyl ether / Ambient temperature View Scheme
参考文献
Parrini,V. et al.
Gazzetta Chimica Italiana, 1974 , vol. 104, p. 715 - 729
反应条件
1: H2 / Pd/C / ethanol / Ambient temperature 2: diethyl ether / Ambient temperature View Scheme
参考文献
Parrini,V. et al.
Gazzetta Chimica Italiana, 1974 , vol. 104, p. 715 - 729
反应条件
1: ethanol / 5 h / Heating 2: H2 / Pd/C / ethanol / Ambient temperature 3: diethyl ether / Ambient temperature View Scheme
参考文献
Parrini,V. et al.
Gazzetta Chimica Italiana, 1974 , vol. 104, p. 715 - 729
反应条件
1: acetic acid anhydride; ZnCl2 View Scheme
参考文献
Cui, Sheng-Feng; Ren, Yu; Zhang, Shao-Lin; Peng, Xin-Mei; Damu, Guri L.V.; Geng, Rong-Xia; Zhou, Cheng-He
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 11 p. 3267 - 3272
反应条件
acetic anhydride; zinc(II) chloride 1.) reflux, 5 h, 2.) reflux, 30 min; Yield given. Multistep reaction;
参考文献
Munoz, Heber; Tamariz, Joaquin; Zamora, Hector Salgado; Lazaro, Miguel; Labarrios, Fernando
Synthetic Communications, 1987 , vol. 17, # 5 p. 549 - 554
反应条件
in diethyl ether Ambient temperature;
参考文献
Parrini,V. et al.
Gazzetta Chimica Italiana, 1974 , vol. 104, p. 715 - 729
反应条件
1: paraffin oil / 290 °C 2: aqueous NaOH View Scheme
参考文献
Duffin; Kendall
Journal of the Chemical Society, 1948 , p. 893
反应条件
1.1: Dowtherm-A / ethanol / 250 - 260 °C 2.1: sodium hydroxide; hydrogenchloride / methanol / 2.5 °C / |Reflux 2.2: Dowtherm-A / 250 - 260 °C View Scheme
参考文献
Yang, Donglai; Arifhodzic, Lejla; Ganellin, C. Robin; Jenkinson, Donald H.
European Journal of Medicinal Chemistry, 2013 , vol. 63, p. 907 - 923
反应条件
in diphenylether T=220 - 250°C;
参考文献
El-Essawy, Farag A.; El-Sayed, Wael A.
Journal of Heterocyclic Chemistry, 2013 , vol. 50, # SUPPL.1 p. E1-E8