2-(3-羟基丙基)氨基吡啶合成路线 （共 8 条）
反应条件
cyclohexene; palladium on activated charcoal in ethanol 48 h; Heating;
参考文献
Marugan, Juan Jose; Manthey, Carl; Anaclerio, Beth; Lafrance, Lou; Lu, Tianbao; Markotan, Tom; Leonard, Kristi A.; Crysler, Carl; Eisennagel, Stephen; Dasgupta, Malini; Tomczuk, Bruce
Journal of Medicinal Chemistry, 2005 , vol. 48, # 4 p. 926 - 934
反应条件
in methanol; ethanol; dichloromethane; cyclohexene
参考文献
3-Dimensional Pharmaceuticals, Inc.
Patent: US2002/169200 A1, 2002 ;
反应条件
T=150°C; Inert atmosphere;
参考文献
SMITHKLINE BEECHAM CORPORATION
Patent: WO2009/111679 A2, 2009 ;
Location in patent: Page/Page column 9; 12 ;
参考文献
Heckmann, Dominik; Meyer, Axel; Marinelli, Luciana; Zahn, Grit; Stragies, Roland; Kessler, Horst
Angewandte Chemie - International Edition, 2007 , vol. 46, # 19 p. 3571 - 3574
参考文献
Yanko; Mosher; Whitmore
Journal of the American Chemical Society, 1945 , vol. 67, p. 666
反应条件
tetrahydrofuran; lithium aluminium tetrahydride
参考文献
Tupin et al.
Bulletin de la Societe Chimique de France, 1957 , p. 721,723
反应条件
1: acetic acid anhydride 2: aq.-ethanolic NaOH 3: LiAlH4; THF View Scheme
参考文献
Tupin et al.
Bulletin de la Societe Chimique de France, 1957 , p. 721,723
反应条件
1: aq.-ethanolic NaOH 2: LiAlH4; THF View Scheme
参考文献
Tupin et al.
Bulletin de la Societe Chimique de France, 1957 , p. 721,723
