4-(1,3-二氧戊环-2-基)苯胺合成路线 （共 14 条）
反应条件
hydrogen; platinum(IV) oxide in tetrahydrofuran
参考文献
Riddle, Justin A.; Jiang, Xuan; Huffman, John; Lee, Dongwhan
Angewandte Chemie - International Edition, 2007 , vol. 46, # 37 p. 7019 - 7022
反应条件
1: 90 percent / p-toluenesulfonic acid / benzene / 4.5 h / Heating 2: H2; CH(OEt)3 / PtO2 / tetrahydrofuran / 1.5 h / 5320.36 Torr View Scheme
参考文献
Chemistry - A European Journal, , vol. 13, # 13 p. 3787 - 3795
反应条件
1: With toluene-4-sulfonic acid in toluene 2 h; Heating / reflux; 2: With hydrogen; palladium 10 on activated carbon in ethanol T=20°C; 4 h;
参考文献
US6667342 B1, ;
Page column 75 ;
US 6667342 B1
反应条件
toluene-4-sulfonic acid; trimethyl orthoformate; PtO2 in tetrahydrofuran; H2; water; ethylene glycol; toluene
反应条件
potassium hydroxide in 1,4-dioxane; water 2.5 h; Heating;
参考文献
Witek, Stanislaw; Bielawski, Jacek; Bielawska, Alicja
Polish Journal of Chemistry, 1981 , vol. 55, # 11 p. 2315 - 2326
反应条件
pyridine in diethyl ether T=0°C; 2 h;
参考文献
Witek, Stanislaw; Bielawski, Jacek; Bielawska, Alicja
Polish Journal of Chemistry, 1981 , vol. 55, # 11 p. 2315 - 2326
反应条件
1: With pyridine in dichloromethane T=0 - 20°C; 16.5 h; 2: With hydrogenchloride in water pH=1;
参考文献
UNION CARBIDE CHEMICALS and PLASTICS TECHNOLOGY CORPORATION
Patent: WO2005/77884 A2, 2005 ;
Location in patent: Page/Page column 17 ;
反应条件
1: pyridine / CH2Cl2 / 16 h / 0 - 20 °C 2: 930 mg / aq. HCl View Scheme
参考文献
Briggs, John R.; Klosin, Jerzy; Whiteker, Gregory T.
Organic Letters, 2005 , vol. 7, # 22 p. 4795 - 4798
反应条件
Yield given. Multistep reaction;
参考文献
Walton, Richard; Lahti, Paul M.
Synthetic Communications, 1998 , vol. 28, # 6 p. 1087 - 1092
反应条件
pyridine in diethyl ether
T=0°C; 0.333333 h;
参考文献
SMITHKLINE BEECHAM CORPORATION
Patent: WO2004/9602 A1, 2004 ;
Location in patent: Page 74 ;
WO 2004/009602 A1
