7-溴-1-苯并噻吩-2-羧酸合成路线 （共 4 条）
参考文献
BAYER HEALTHCARE AG
Patent: WO2003/104227 A1, 2003 ;
Location in patent: Page 47, 48 ;
参考文献
WO2003/104227 A1, ;
Page 47 ;
反应条件
borane-THF T=60°C; 3 h; Cooling with ice;
参考文献
Takeda Pharmaceutical Company Limited
Patent: US2010/41891 A1, 2010 ;
Location in patent: Page/Page column 63 ;
US 20100041891 A1
反应条件
diphenyl phosphoryl azide; N-ethyl-N,N-diisopropylamine in water; N,N-dimethyl-formamide
T=0 - 8°C;
参考文献
Luithle, Joachim; Boss, Frank-Gerhard; Erb, Christina; Flessner, Timo; Hendrix, Martin; Kampen, Marja van; Methfessel, Christoph
Patent: US2005/107460 A1, 2005 ;
Location in patent: Page/Page column 6 ;
