1,3,5-三-(叠氮基甲基)-2,4,6-三乙基苯合成路线 （共 7 条）
反应条件
water; triphenylphosphine in tetrahydrofuran T=20°C;
参考文献
Cabell, Larry A.
Journal of the Chemical Society, Perkin Transactions 2, 2001 , # 3 p. 315 - 323
反应条件
N,N'-dimethyl-N,N'-propyleneurea; sodium azide
T=80°C; 12 h;
参考文献
Ryu, Eui-Hyun; Yan, Jie; Zhong, Zhenqi; Zhao, Yan
Journal of Organic Chemistry, 2006 , vol. 71, # 19 p. 7205 - 7213
反应条件
1: HOAc; HBr
2: HOAc; KBr; H2SO4
3: NaN3 / ethanol; H2O / Heating
View Scheme
参考文献
Capitan-Vallvey, Luis Fermin; Arroyo-Guerrero, Eduardo; Fernandez-Ramos, Maria Dolores; Santoyo-Gonzalez
Analytical Chemistry, 2005 , vol. 77, # 14 p. 4459 - 4466
反应条件
sodium azide in water; acetone
16 h; Heating;
参考文献
Kilway, Kathleen V; Siegel, Jay S
Tetrahedron, 2001 , vol. 57, # 17 p. 3615 - 3627
反应条件
1: HOAc; KBr; H2SO4
2: NaN3 / ethanol; H2O / Heating
View Scheme
参考文献
Capitan-Vallvey, Luis Fermin; Arroyo-Guerrero, Eduardo; Fernandez-Ramos, Maria Dolores; Santoyo-Gonzalez
Analytical Chemistry, 2005 , vol. 77, # 14 p. 4459 - 4466
反应条件
sodium azide in N,N-dimethyl-formamide
T=25°C; Substitution; 24 h;
参考文献
Niikura, Kenichi; Anslyn, Eric V.
Journal of the Chemical Society. Perkin Transactions 2, 1999 , # 12 p. 2769 - 2775
反应条件
1: 90 percent / AlCl3 / 12 h / 0 - 20 °C
2: 70 percent / HBr; Zn; AcOH / 48 h / 90 °C
3: aq. NaN3 / dimethylformamide; CH2Cl2 / 22 h
View Scheme
参考文献
Wallace, Karl J.; Hanes, Robert; Anslyn, Eric; Morey, Jeroni; Kilway, Kathleen V.; Siegel, Jay
Synthesis, 2005 , # 12 art. no. M09004SS, p. 2080 - 2083
