2,3-二氢-2-甲基-3-亚甲基吡嗪并[1,2-a]吲哚-1,4-二酮合成路线 （共 3 条）
反应条件
aluminum oxide in benzene 12 h; Ambient temperature;
参考文献
Johns, Nicholas; Kirby, Gordon W.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 1487 - 1490
反应条件
1: 1.) Sn, HCl; 2.) CH3NH2 / 1.) H2O; 2.) H2O 2: 1.) diisopropylethylamine; 2.) 2,3-dichloro-5,6-dicyano-1,4-benzoquinone, p-toluenesulphonic acid, Tos-OH / 1.) r.t., CCl4, CH2Cl2, 1 h; 2.) dioxane, reflux, 16 h View Scheme
参考文献
Herscheid, Jacobus D. M.; Scholten, Henk P. H.; Tijhuis, Marian W.; Ottenheim, Harry C. J.
Recueil: Journal of the Royal Netherlands Chemical Society, 1981 , vol. 100, # 2 p. 73 - 78
反应条件
toluene-4-sulfonic acid; N-ethyl-N,N-diisopropylamine; 2,3-dicyano-5,6-dichloro-p-benzoquinone 1.) r.t., CCl4, CH2Cl2, 1 h; 2.) dioxane, reflux, 16 h; Yield given. Multistep reaction;
参考文献
Herscheid, Jacobus D. M.; Scholten, Henk P. H.; Tijhuis, Marian W.; Ottenheim, Harry C. J.
Recueil: Journal of the Royal Netherlands Chemical Society, 1981 , vol. 100, # 2 p. 73 - 78
