1-Cbz-4-哌啶酮合成路线

19099-93-51-Cbz-4-哌啶酮

1147998-34-24-(三甲基硅基氧基)-5,6-二氢吡啶-1(2H)-甲酸苄酯

参考文献

WO2012/66077 A1, ;

Page/Page column 22 ;
WO 2012/066077 A1

19099-93-51-Cbz-4-哌啶酮

参考文献

Hendricks, Robert Than; Hermann, Johannes; Kondru, Rama; Lou, Yan; Lynch, Stephen M.; Owens, Timothy D.; Soth, Michael
Patent: US2011/230462 A1, 2011 ;
US 20110230462 A1

19099-93-51-Cbz-4-哌啶酮

185961-99-31,3-二氢-1-(4-哌啶基)-2H-咪唑并[4,5-b]吡啶-2-酮

参考文献

BOEHRINGER INGELHEIM INTERNATIONAL GMBH
Patent: US2012/88755 A1, 2012 ;

19099-93-51-Cbz-4-哌啶酮

280111-51-54-肼基哌啶-1-羧酸苄酯

参考文献

Chiesi Farmaceutici S.p.A.; Van Niel, Monique Bodil; Ray, Nicholas Charles; Cridland, Andrew Peter; Hurley, Christopher; Alcaraz, Lilian; Panchal, Terry Aaron; Jennings, Andrew Stephen Robert; Armani, Elisabetta
Patent: US2013/150361 A1, 2013 ;
Location in patent: Paragraph 0446; 0447 ;

19099-93-51-Cbz-4-哌啶酮+

57260-73-8N-叔丁氧羰基-1,2-乙二胺

72349-01-04-(2-氧代咪唑啉-1-基)哌啶-1-羧酸苄酯

参考文献

AMGEN INC.
Patent: WO2009/78992 A1, 2009 ;
Location in patent: Page/Page column 42-43 ;
WO 2009/078992 A1

19099-93-51-Cbz-4-哌啶酮

725228-49-93-(哌啶-4-基)苄基氨基甲酸叔丁酯

参考文献

CORNELL UNIVERSITY; COFERON, INC.; PURDUE RESEARCH FOUNDATION
Patent: US2012/295874 A1, 2012 ;
US 20120295874 A1

19099-93-51-Cbz-4-哌啶酮+

4637-24-5N,N-二甲基甲酰胺二甲基缩醛

727382-73-2

参考文献

Petersen, Jette G.; Bergmann, Rikke; Moller, Henriette A.; Jorgensen, Charlotte G.; Nielsen, Birgitte; Kehler, Jan; Frydenvang, Karla; Kristensen, Jesper; Balle, Thomas; Jensen, Anders A.; Kristiansen, Uffe; Frolund, Bente
Journal of Medicinal Chemistry, 2013 , vol. 56, # 3 p. 993 - 1006

19099-93-51-Cbz-4-哌啶酮+

5815-08-7

727382-73-2

参考文献

Gomez, Laurent; Hack, Michael D.; Wu, Jiejun; Wiener, John J.M.; Venkatesan, Hari; Santillan Jr., Alejandro; Pippel, Daniel J.; Mani, Neelakandha; Morrow, Brian J.; Motley, S. Timothy; Shaw, Karen Joy; Wolin, Ronald; Grice, Cheryl A.; Jones, Todd K.
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 10 p. 2723 - 2727

19099-93-51-Cbz-4-哌啶酮

65535-86-6

参考文献

Tai, Vincent W.-F.; Garrido, Dulce; Price, Daniel J.; Maynard, Andrew; Pouliot, Jeffrey J.; Xiong, Zhiping; Seal, John W.; Creech, Katrina L.; Kryn, Luz H.; Baughman, Todd M.; Peat, Andrew J.
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 10 p. 2288 - 2294

19099-93-51-Cbz-4-哌啶酮

59022-45-6

参考文献

Chang, Meng-Yang; Pai, Chun-Li; Kung, Yung-Hua
Tetrahedron Letters, 2005 , vol. 46, # 49 p. 8463 - 8465