1-Cbz-4-哌啶酮合成路线

19099-93-51-Cbz-4-哌啶酮

6786-41-0螺[3H-吲哚-3,3'-吡咯烷]-2(1H)-酮

参考文献

Chang, Meng-Yang; Pai, Chun-Li; Kung, Yung-Hua
Tetrahedron Letters, 2005 , vol. 46, # 49 p. 8463 - 8465

867-13-0膦酰乙酸三乙酯+

19099-93-51-Cbz-4-哌啶酮

82244-11-94-(2-乙氧基-2-氧代亚乙基)哌啶-1-羧酸苄酯

参考文献

ASTRAZENECA AB
Patent: WO2008/147314 A1, 2008 ;
Location in patent: Page/Page column 63 ;
WO 2008/147314 A1

19099-93-51-Cbz-4-哌啶酮+

1099-45-2乙氧甲酰基亚甲基三苯基膦

82244-11-94-(2-乙氧基-2-氧代亚乙基)哌啶-1-羧酸苄酯

参考文献

ASTRAZENECA AB
Patent: WO2008/147314 A1, 2008 ;
Location in patent: Page/Page column 63 ;
WO 2008/147314 A1

19099-93-51-Cbz-4-哌啶酮+

107-91-5氰乙酰胺

869278-52-4

参考文献

Jennings, Lee D.; Kincaid, Scott L.; Wang, Yanong D.; Krishnamurthy, Girija; Beyer, Carl F.; McGinnis, John P.; Miranda, Miriam; Discafani, Carolyn M.; Rabindran, Sridhar K.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 21 p. 4731 - 4735

19099-93-51-Cbz-4-哌啶酮

880462-12-44-(4-氧代哌啶-1-基)哌啶-1-羧酸苄酯

参考文献

Semetey, Vincent; Moustakas, Demetri; Whitesides, George M.
Angewandte Chemie - International Edition, 2006 , vol. 45, # 4 p. 588 - 591

19099-93-51-Cbz-4-哌啶酮+

159603-71-12-BOC-氨基-6-氯吡啶

883984-95-0

参考文献

BOEHRINGER INGELHEIM INTERNATIONAL GMBH
Patent: US2012/149698 A1, 2012 ;
Location in patent: Page/Page column 26 ;

19099-93-51-Cbz-4-哌啶酮

883984-95-0

参考文献

MERCK and CO., INC.
Patent: WO2007/16087 A2, 2007 ;
Location in patent: Page/Page column 49; 66 ;
WO 2007/016087 A2

19099-93-51-Cbz-4-哌啶酮

91157-43-6

参考文献

Borne, Ronald F.; Fifer, E. Kim; Waters, I.W.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 10 p. 1271 - 1275

19099-93-51-Cbz-4-哌啶酮

43139-18-04-异丙氧基哌啶

参考文献

Kuethe, Jeffrey T.; Janey, Jacob M.; Truppo, Matthew; Arredondo, Juan; Li, Tao; Yong, Kelvin; He, Shuwen
Tetrahedron, 2014 , vol. 70, # 30 p. 4563 - 4570

19099-93-51-Cbz-4-哌啶酮

586375-35-14-甲基-4-羟基哌啶盐酸盐

参考文献

Takeda Pharmaceutical Company Limited
Patent: EP2392573 A1, 2011 ;