1,4-苯二氧杂环乙烷-6-腈合成路线 (共 3 条)
反应条件
lithium hydride in dimethyl sulfoxide T=110°C; 1.5 h;
参考文献
Deshmukh, Mahesh S.; Das, Biswajit; Jain, Nidhi
RSC Advances, 2013 , vol. 3, # 44 p. 22389 - 22396
反应条件
caesium carbonate; triphenylphosphine; palladium dichloride in toluene T=50°C; 24 h;
参考文献
Jing, Xiaobi; Shi, Yaocheng; Liu, Yonghong; Han, Ying; Yan, Chaoguo; Wang, Li
Synthetic Communications, 2004 , vol. 34, # 9 p. 1723 - 1727
反应条件
1: 99 percent / TBAF / tetrahydrofuran / 0.5 h / 0 °C 2: 84 percent / Pd(OAc)2; Cs2CO3; 9-(2-di-tert-butylphosphanylphenyl)phenanthrene / toluene / 48 h / 50 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 122, # 51 p. 12907 - 12908