(R)-1,2,3,4-四氢-3-异喹啉羧酸甲酯合成路线 （共 3 条）
反应条件
trifluoroacetic acid in dichloromethane T=20°C; 1 h;
参考文献
Charton, Julie; Gassiot, Amaury Cazenave; Girault-Mizzi, Sophie; Debreu-Fontaine, Marie-Ange; Melnyk, Patricia; Sergheraert, Christian
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 21 p. 4833 - 4837
反应条件
1.1: aq. Cs2CO3 / methanol / 0.17 h / 20 °C 1.2: dimethylformamide / 12 h / 20 °C 2.1: TFA / CH2Cl2 / 1 h / 20 °C View Scheme
参考文献
Charton, Julie; Gassiot, Amaury Cazenave; Girault-Mizzi, Sophie; Debreu-Fontaine, Marie-Ange; Melnyk, Patricia; Sergheraert, Christian
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 21 p. 4833 - 4837
反应条件
1.1: aq. NaOH / dioxane / 20 °C 2.1: aq. Cs2CO3 / methanol / 0.17 h / 20 °C 2.2: dimethylformamide / 12 h / 20 °C 3.1: TFA / CH2Cl2 / 1 h / 20 °C View Scheme
参考文献
Charton, Julie; Gassiot, Amaury Cazenave; Girault-Mizzi, Sophie; Debreu-Fontaine, Marie-Ange; Melnyk, Patricia; Sergheraert, Christian
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 21 p. 4833 - 4837
