4,5,6,7-四氢苯并[b]噻吩-3-羧酸合成路线 （共 2 条）
反应条件
sodium hydroxide in ethanol 0.5 h; Heating;
参考文献
Mitsumori, Susumu; Tsuri, Tatsuo; Honma, Tsunetoshi; Hiramatsu, Yoshiharu; Okada, Toshihiko; Hashizume, Hiroshi; Inagaki, Masanao; Arimura, Akinori; Yasui, Kiyoshi; Asanuma, Fujio; Kishino, Junji; Ohtani, Mitsuaki
Journal of Medicinal Chemistry, 2003 , vol. 46, # 12 p. 2446 - 2455
反应条件
1.1: aq. NaNO2; HCl / dioxane / 0.25 h / -5 °C 1.2: 54 percent / aq. H3PO4 / diethyl ether / 0.5 h / 0 °C 2.1: 97 percent / aq. NaOH / ethanol / 0.5 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 46, # 12 p. 2446 - 2455
