2-甲氧基-5-(三氟甲氧基)苯甲酸合成路线 （共 5 条）
反应条件
hydrogenchloride; sodium hydroxide; acetic acid in hexane; water; tert-butyl alcohol
反应条件
1: 1-methoxy-4-trifluoromethoxybenzene With tert.-butyl lithium in tetrahydrofuran; pentane T=-75°C; 2 h; 2: carbon dioxide in tetrahydrofuran; pentane Further stages.;
参考文献
Castagnetti, Eva; Schlosser, Manfred
Chemistry - A European Journal, 2002 , vol. 8, # 4 p. 799 - 804
反应条件
1: 2-bromo-1-methoxy-4-trifluoromethoxy-benzene With n-butyllithium in diethyl ether; hexane T=-78°C; 0.333333 h; 2: carbon dioxide in diethyl ether; hexane 0.166667 h;
参考文献
US2005/261342 A1, ;
Page/Page column 11 ;
US 20050261342 A1
反应条件
1: 1-methoxy-4-trifluoromethoxybenzene With N,N,N',N'',N''-pentamethylethylenetriamine; sec.-butyllithium in tetrahydrofuran; hexane T=-75°C; 2 h; 2: carbon dioxide in tetrahydrofuran; hexane
参考文献
Castagnetti, Eva; Schlosser, Manfred
Chemistry - A European Journal, 2002 , vol. 8, # 4 p. 799 - 804
反应条件
1: With boron tribromide in dichloromethane T=0°C; 16 h; 2: With hydrogenchloride in dichloromethane; water pH=0;
参考文献
US2005/261342 A1, ;
Page/Page column 11 ;
US 20050261342 A1
