2,1,3-苯噁二唑-5-甲醛 1-氧化物合成路线 （共 7 条）
反应条件
sodium azide; benzyl-tri-(n-butyl)-ammonium bromide in 1,2-dichloro-ethane T=25 - 60°C;
参考文献
Jorge, Salomao Doria; Masunari, Andrea; Rangel-Yagui, Carlota Oliveira; Pasqualoto, Kerly Fernanda Mesquita; Tavares, Leoberto Costa
Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 8 p. 3028 - 3036
反应条件
manganese(IV) oxide in chloroform 2 h; Ambient temperature;
参考文献
Gasco; Ermondi; Fruttero
European Journal of Medicinal Chemistry, 1996 , vol. 31, # 1 p. 3 - 10
反应条件
in toluene 0.5 h; Reflux;
参考文献
Jorge, Salomao Doria; Masunari, Andrea; Rangel-Yagui, Carlota Oliveira; Pasqualoto, Kerly Fernanda Mesquita; Tavares, Leoberto Costa
Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 8 p. 3028 - 3036
反应条件
1: 75 percent / N-bromosuccinimide, benzoyl peroxide / CCl4 / 4 h / Heating 2: 75 percent / water, calcium carbonate / dioxane / 3 h / Heating 3: 92 percent / manganese dioxide / CHCl3 / 2 h / Ambient temperature View Scheme
参考文献
Gasco; Ermondi; Fruttero
European Journal of Medicinal Chemistry, 1996 , vol. 31, # 1 p. 3 - 10
反应条件
1: 75 percent / water, calcium carbonate / dioxane / 3 h / Heating 2: 92 percent / manganese dioxide / CHCl3 / 2 h / Ambient temperature View Scheme
参考文献
Gasco; Ermondi; Fruttero
European Journal of Medicinal Chemistry, 1996 , vol. 31, # 1 p. 3 - 10
反应条件
(i) NaNO2, H2SO4, AcOH, (ii) aq. NaN3, (iii) (heating), toluene; Multistep reaction;
参考文献
Ghosh; Ternai; Whitehouse
Journal of medicinal chemistry, 1972 , vol. 15, # 3 p. 255 - 260
反应条件
n-butyllithium in tetrahydrofuran
T=0°C;
参考文献
Porcal, Williams; Hernandez, Paola; Boiani, Mariana; Aguirre, Gabriela; Boiani, Lucia; Chidichimo, Agustina; Cazzulo, Juan J.; Campillo, Nuria E.; Paez, Juan A.; Castro, Ana; Krauth-Siegel, R. Luise; Davies, Carolina; Basombrio, Miguel Angel; Gonzalez, Mercedes; Cerecetto, Hugo
Journal of Medicinal Chemistry, 2007 , vol. 50, # 24 p. 6004 - 6015
